Treatment consisted of intravesical instillation of rhGM-(400 microg) for 3 consecutive days. A complete response was observed in three patients, the other three showed a partial response. Median time to achieve response was 36 h (range 0.2-72 h). Hematuria was controlled after the first (...
This case is of a 26 year old female evaluated for gross hematuria and suprapubic pain found to have a large bladder tumor. She subsequently underwent successful robotic assisted laparoscopic partial cystectomy. Pathology revealed pseudosarcomatous fibromyxoid tumor, an uncommon lesion that occurs most...
Serious adverse reactions occurred in 42% of patients; those ≥2% were urinary tract infection, hematuria, acute kidney injury, pneumonia, and urosepsis. The most common adverse reactions (≥20%) were fatigue ...
In KEYNOTE-052, KEYTRUDA was discontinued due to adverse reactions in 11% of 370 patients with locally advanced or metastatic urothelial carcinoma. Serious adverse reactions occurred in 42% of patients; those ≥2% were urinary tract inf...
Urinalysis is an extremely effective method of screening for Alport syndrome. All males with X-linked Alport syndrome, as well as all males and females with autosomal recessive Alport syndrome, have persistent microhematuria. In females who are heterozygous for X-linked Alport syndrome, the likelihoo...
Bleeding from the gastrointestinal tract can lead to blood in the stool. Bleeding from the urinary tract can lead to blood in the urine (hematuria). Intracranial hemorrhage (bleeding into the brain or skull) can lead to symptoms such as nausea, vomiting, and/or lethargy, and can lead to de...
Embryo-Fetal Toxicity –Safety and efficacy of NUBEQA have not been established in females. NUBEQA can cause fetal harm and loss of pregnancy. Advise males with female partners of reproductive potential to use effective contraception during treatment with NUBEQA and for 1 week after the last dose....
In KEYNOTE-052, KEYTRUDA was discontinued due to adverse reactions in 11% of 370 patients with locally advanced or metastatic urothelial carcinoma. Serious adverse reactions occurred in 42% of patients; those ≥2% were urinary tract ...
Of the 350 children (age range four to fifteen years; 186 male, 164 female) enrolled into the study, 245 (70.0%) – 132 males and 113 females – were positive for S. haematobium, determined using the urine filtration technique. The age group of four to nine years had the highest preva...
Serious adverse reactions occurred in 42% of patients; those ≥2% were urinary tract infection, hematuria, acute kidney injury, pneumonia, and urosepsis. The most common adverse reactions (≥20%) were fatigue (38%), musculoskeletal ...