Behavioral and psychological symptoms of dementia (BPSD) in FTD place a heavy burden on caregivers. Treatment with donepezil, reported to delay the progression of Alzheimer's disease (AD), often causes the BPSD in FTD to deteriorate, according to several reports.1'2 The purpose of the ...
Frontotemporal Dementia (FTD) Parkinson’s Disease Dementia Others Dementia Treatment Drug Class Outlook (Revenue, USD Million, 2018 - 2030) Cholinesterase Inhibitors NMDA Receptor Antagonist MAO Inhibitors Combination Drug Others Dementia Treatment Route of Administration Outlook (Revenue, USD ...
Scientists take promising step forward in the treatment of neurodegenerative dementia, according to study.
12 November 2015 Number of times this article has been viewed Taro Kishi Shinji Matsunaga Nakao Iwata Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan Background: There is no conclusive evidence supporting the efficacy of memantine in frontotemporal dementia (FTD)...
Behavioral variant frontotemporal dementia (bvFTD) is a rapidly progressing destructive disease and can occur in people as young as 35 years of age. It is characterized by behavioral disturbances and personality changes and can be highly disruptive and distressing for both patients and their families...
Astellas Pharma and AviadoBio Ltd. have announced an exclusive option and license agreement for AVB-101, an AAV-based gene therapy currently in Phase I/II development for treating frontotemporal dementia with progranulin mutations (FTD-GRN). According to Astellas, the deal gives the ...
www.nature.com/scientificreports OPEN received: 07 January 2015 accepted: 13 May 2015 Published: 08 July 2015 Novel drug target identification for the treatment of dementia using multi-relational association mining Thanh-Phuong Nguyen1,2, Corrado Priami1,3 & Laura Caberlotto1 Dementia is a...
Exosomal microRNAs (miR) and proteins reflect the disease state, and therefore, exosomes can be used as diagnostic markers for diseases such as AD, PD, Huntington's disease (HD), vascular dementia (VaD), dementia with Lewy bodies (DLB), and frontotemporal dementia (FTD). Mesenchymal stem ...
Our unique approach recognises amyotrophic lateral sclerosis (ALS), Parkinson’s disease (PD) and frontotemporal dementia (FTD) as neuro-metabolic diseases, which herald a paradigm shift in the fundamental understanding of the aetiology and development of these diseases. ...
Our results suggest that memantine may benefit FTD patients. However, because only two randomized controlled trials have addressed this issue, further studies using larger samples are needed. 展开 关键词: frontotemporal dementia memantine meta-analysis Clinical Global Impression ...