These case reports have shown that frontal lobe damage often results in antisocial behavior, apathy, disinhibition, and emotional lability. Discrete prefrontal cortex lesions are sometimes associated with unique behavioral profiles. Although numerous exceptions exist, frontal lobe dysfunction exhibits ...
These case reports have shown that frontal lobe damage often results in antisocial behavior, apathy, disinhibition, and emotional lability. Discrete prefrontal cortex lesions are sometimes associated with unique behavioral profiles. Although numerous exceptions exist, frontal lobe dysfunction exhibits ...
Despite widespread use of second-generation cholinesterase inhibitors for the symptomatic treatment of Alzheimer’s disease (AD), little is known about the long term effects of cholinergic treatment on global cognitive function and potential specific effects in different cognitive domains. The objectives ...
Despite widespread use of second-generation cholinesterase inhibitors for the symptomatic treatment of Alzheimer’s disease (AD), little is known about the long term effects of cholinergic treatment on global cognitive function and potential specific effects in different cognitive domains. The objectives ...
103 In addition, activated microglia produce several neurotoxic substances, such as free radicals and proinflammatory cytokines that can damage neuronal and glial cells, leading to cognitive dysfunction and brain volume loss.100 Neuroinflammation and NMDAr dysfunction are interwoven in several ways. For ...
Orbitofrontal contributions to value-based decision making: evidence from humans with frontal lobe damage. Ann N. Y Acad Sci. 2011;1239:51–8. Article PubMed Google Scholar Noonan MP, Chau BKH, Rushworth MFS, Fellows LK. Contrasting Effects of Medial and Lateral Orbitofrontal Cortex Lesions ...
Other neurologic disorders less commonly associated with dementia include normal pressure hydrocephalus, subdural hematoma, brain tumor, posttraumatic brain injury, and posthypoxic damage. Diagnostic evaluation A diagnostic evaluation for dementia involves a complete history, neuropsychological examination (eg, ...
(cAMP response element-binding protein) and Na+-K+ATPase. Genetic and pharmacogenetic studies are starting to generate promising findings, but remain limited by small sample sizes. As full responders to lithium seem to represent a unique clinical population, there is inherent value and need for ...
"When adolescents become addicted to drugs, serious brain damage occurs in a shorter time and at a lower dose than adults," she said. "Damage to the frontal lobe, which controls emotions, leads to depression, anxiety, and impulsive mood swings, as well as cognitive decline, such as difficul...
(MAS): Fatal HLH occurred in one patient (1%), 99 days after ciltacabtagene autoleucel. The HLH event was preceded by prolonged CRS lasting 97 days. The manifestations of HLH/MAS include hypotension, ...