Dyskinesias encompass a variety of different hyperkinetic phenomenologies, particularly chorea, dystonia, stereotypies, and akathisia. Levodopa-induced dyskinesia (LID) is one of the main types of drug-induced dyskinesia, occurring in patients with Parkinson's disease (PD) who have been treated ...
BackgroundAntipsychotics remain the mainstay of drug intervention in the management of schizophrenia. However, long-term treatment with antipsychotics is
The high priced drug overdose showed severe EPS includes dystonia and severe muscle tension, as well as hypotension and sedation. The low potency drugs appeared more CNS suppression and sedation, Anticholinergic and hypotension can be seen clinically with agitation, restlessness, convulsions, fever, ...
Sodium oxybate, which is a sodium salt of gamma-hydroxybutyric acid, has been found to be effective in a single-blinded clinical trial, which included 3 patients with myoclonus–dystonia syndromes [46]. As previously described above in discussion of sodium oxybate use for cortical forms of ...
Although visual loss is the defining feature of this mitochondrial disorder, cardiac conduction defects and neurological abnormalities such as ataxia, peripheral neuropathy, myopathy, and dystonia have been reported to be more common among LHON carriers compared with controls.1, 2 However, because of ...
In these situations, treating the underlying reason for the complement activation may be the most beneficial course of action [79]. BTH due to subtherapeutic drug levels is relatively common with eculizumab, and many patients need to be treated with doses that are higher than the approved label...
iatrogenic problems are mostly related to drug-induced extrapyramidal side effects, including drug-induced parkinsonism, dystonia, and tardive dyskinesia, but may also include xerostomia, sialorrhea, and changes related to sedation. Dysphagia is a prevalent difficulty among aging adults. Antipsychotic ...
If clozapine doesn’t work, you have other options. Your doctor might suggest combining two or more antipsychotic drugs. They also could add a drug to keep your mood stable. Using multiple drugs can raise your risk for side effects, so only try this with your doctor’s guidance. ...
was used to investigate spatial memory in models of dementia, the Forced Swimming Test was used for assessing immobility (as a measure of behaviour despair) in models of depression, and the Drug Self-Administration paradigm was used in substance use disorder models. Moreover, quantification of ...
Leukopenia, Neutropeniaand Agranulocytosishave been reported with antipsychotic agents, including risperidone. In patients with a pre-existing history of a clinically significant low white blood cell count (WBC) or absolute neutrophil count (ANC) or a history of drug-induced leukopenia or neutropenia,...