It has also occasionally caused hypersensitivity reactions and a deficiency of platelets, which are the blood components responsible for clotting. Either of these reactions can be fatal. Quinine is also associated with a cluster of symptoms called cinchonism (nausea, vomiting, headaches, and deafness...
Coughing or vomiting too hard Doing intense physical activity, like working out or playing sports, without taking time to rest and recover Doing physical activity that you don't normally do, like increasing the intensity of your workout too fast or moving furniture ...
The invention relates to substituted ureas, and compositions comprising the same, which in certain embodiments are useful for treating and/or preventing pain in a subject in need thereof. Inventors: TOUNGE BRETT A (US) BAYOUMY SHARIFF (US) KUO LAWRENCE C (US) DAX SCOTT (US) Application...
There is further provided the use of the compounds of the invention in the manufacture of a medicament for the treatment of irritable bowel syndrome; constipation; nausea; vomiting; pruritus or a medical condition characterised by pruritus as a symptom....
Dog641.710.5 (8 kg) Human127321 (60 kg) Desirable blood levels may be maintained by a continuous infusion of an arsenic compound as ascertained by plasma levels. It should be noted that the attending physician would know how to and when to terminate, interrupt or adjust therapy to lower do...
in the form of a sterile aqueous solution or dispersion suitable for administration by either direct injection or by addition to sterile infusion fluids for intravenous infusion; or in the form of a lotion, cream, foam, patch, suspension, solution, or suppository for transdermal or transmucosal ...
The longest half-life was in human hepatocytes, followed by dog, then monkey and then rat. The half-lives range from 10-30 hours for Formula IV and 8-23 hours for the triphosphate of Sovaldi. Further, as described in Example 17 and FIGS. 2 and 3, over a 48 hour period, while the...