Decreased bone density and treatment in patients with autosomal recessive cutis laxa. Acta Paediatr 2009;98:390-3.Noordam C, Funke S, Knoers NV, Jira P, Wevers RA, Urban Z, Morava E (2009) Decreased bone density and treatment in patients with autosomal recessive cutis laxa. Acta Paediatr...
Abstract Importance As men age, they experience decreased serum testosterone concentrations, decreased bone mineral density (BMD), and increased risk of fracture. Objective To determine whether testosterone treatment of older men with low testosterone increases volumetric BMD (vBMD) and estimated bone str...
BoneO'Sullivan S, Horne A, Wattie D, et al. Decreased bone turnover despite persistent secondary hyperparathyroidism during prolonged treatment with imatinib. J Clin Endocrinol Metab 2009;94:1131-1136.O'Sullivan S, Horne A, Wattie D, Porteous F, Callon K, Gamble G, et al. Decreased bone ...
72,73 Over the years, the number of embryos transferred in IVF has decreased globally, but two to three embryos are still transferred in a significant proportion of IVF cycles in many countries around the world. On the basis of a large nationwide data set from the United Kingdom, it wa...
Additionally, the medium dose of ButM modestly decreased the neutrophil score (Fig. 8d) and the low dose modestly decreased the hyperplasia score (Fig. 8e) in the distal colon. These results show that ButM reduces disease severity in the CD45RBhi T-cell-transfer model of colitis, and ...
Osteoporosis is a global health problem for ageing populations. The goals of osteoporosis treatment are to improve bone mineral density (BMD) and prevent fractures. One major obstacle that remains a great challenge to achieve the goals is how to select the best treatment regimen for individual pati...
Glucocorticoids (GCs) are prescribed for the treatment of several diseases, but their long-term use causes osteoporosis. Current research suggests that GCs suppress the canonical Wnt/beta pathway, resulting in decreased expression of critical bone proteins. This study examined how bone structure and st...
The results showed that the initial body mass index (BMI) and hemoglobin A1c (HbA1c) decreased, density lipoprotein cholesterol (HDL-C) increased in both groups. Still, the change was significantly greater in the IL-I group after six months. They believe that lifestyle changes, including ...
Pre-administration of bevacizumab (Avastin®) 1–3 days before topotecan/etoposide administration to neuroblastoma patients, induced vascular normalization (decreased vessel density and improved tumor perfusion) and enhanced tumor uptake of topotecan and etoposide. However, simultaneous co-administration the...
(GO)82. Decreased GO enzyme levels in the body result in reduction of plasma and urinary oxalate levels, the underlying cause for the symptoms in patients with PH1. A phase 3 trial (ILLUMINATE-A, NCT03681184) was conducted in a cohort of 39 patients (lumasiran groupn = 26 and ...