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Exclusion criteria included: idiopathic VT not causing depressed ventricular dysfunction, protruding left ventricle (LV) thrombus, myocardial infarction within 2 months, Class IV heart failure or cardiogenic shock unless due to VT, contraindication to heparin, allergy to radiographic contrast dye, severe ...
1Department of Radiation Oncology; 2Department of Surgery, Division of Thoracic Surgery; 3Department of Medicine, Division of Medical Oncology; 4Department of Medicine, Division of Pulmonary, Allergy and Critical Care ABSTRACT KEY WORDS Photodynamic therapy is increasingly being utilized to treat thoracic...
The conclusions of TB APPRISE and the BRIEF TB secondary analysis contrast with those from observational studies of pregnant people living with HIV in South Africa [83, 92]. In these studies, isoniazid given for TPT was not associated with an increased risk of adverse pregnancy outcomes. A ...
Gut microbial dysbiosis and leaky gut play a role in systemic lupus erythematosus (SLE). Geographical location and dietary habits affect the microbiome composition in diverse populations. This study explored the gut microbiome dysbiosis, leaky gut, and s
A safer treatment for toxoplasmosis would be achieved by improving the selectivity and potency of dihydrofolate reductase (DHFR) inhibitors, such as pyrimethamine (1), for Toxoplasma gondii DHFR (TgDHFR) relative to human DHFR (hDHFR). We previously reported on the identification of meta-biphenyl ...
In contrast, for this scenario, only 3% of overall infections were averted in Mexico, which had a high vaccination coverage but had not been boosted the population at that time, and 2% of the overall infections were averted in Kenya. Indeed with very limited vaccine supply, the effective ...
to epsilon (ε) heavy chain of IgE, with said target antigenic site covalently linked to (1) a carrier protein through chemical coupling, or (2) a helper T cell epitope and other immunostimulatory sequences through chemical coupling or through direct synthesis, for the treatment of allergy. ...
is augmented in Th17 cell, but not Th1, cell responses, and Tregcells can restrain these Th17 cell responses in an IL-10-dependent manner. Thus, homeostatic Th17 cells have the profile of IL-17+/IL-10+; in contrast, pathogenic Th17 cells have the profile of IL-17+/IL-10−/IFNγ+...
The present invention relates to compositions for preventing or treating allergy to ragweed by tolerization. The compositions are based on combinations of peptide fragments derived