but it can also occur in older adults. The most likely locations for developing osteosarcoma are in the long bones of the arms and legs near the growth regions of the knees and shoulders. This is often a very aggressive cancer, and it can spread (metastasize) to other...
This treatment has been shown to reduce the risk of recurrence and death from breast cancer in hormone receptor-positive women. These are usually oral medications taken daily for 5 to 10 years.The side effects of hormonal therapy depend largely on the specific drug or type of treatment. For ...
Breast carcinoma is the most common cancer of women. Bones are often involved with breast carcinoma metastases with the resulting morbidity and reduced quality of life. Breast cancer cells arriving at bone tissues mount supportive microenvironment by recruiting and modulating the activity of several host...
Acute myeloid leukemia (AML) is a type of blood cancer that starts in your bone marrow, which is the soft inner part of your bones where all your blood cells are made. AML usually begins in cells that turn into white blood cells but can also start in other blood-forming cells. When b...
CLL can change from a slow-growing or low-grade cancer to an aggressive and fast-growing or high-grade cancer. Bone pain is a sign that your cancer is growing more quickly. The pain happens when leukemia cells multiply in your bone marrow – the spongy material inside your bones – and ...
1 An increase in the survival time may increase the incidence of bone metastasis. Recently, cancer chemotherapy has also made considerable progress in increasing survival of patients with far-advanced cancer. For example, gefitinib improved disease-free survival of epidermal growth factor receptor (...
Neoplasm recurrenceNeoplasm metastasesDiagnostic imagingAntineoplastic agentsBiosimilar pharmaceuticalsImaging has a central role in surveillance of cervical cancer, guiding decision on when to initiate treatment for recurrent disease and to guide management in advanced cervical cancer. Due to the increased ...
also found that 15D11 could reduce the recurrence of bone metastasis [108]. The mechanism is to destroy the effect of the tumor on the efficacy of chemotherapy by targeting Jagged1, so that the chemotherapy can continue normally. The study also confirmed the effect on bone metastasis of ...
The complications of radiotherapy for breast cancer and the treatment for radiation ulcer. Chin J Plast Surg (Chinese), 2004,(1):13–16 Xu J, Mu L H, Liu Y B et al. Deep inferior epigastric perforator flaps in breast reconstruction and chest wall ulcer repair. Chin J Surg (Chinese), ...
The primary tumor induces early changes in the microenvironment of distant organs that are initially free of cancer cells [61], thereby creating a favorable environment for cancer cell infiltration and metastasis initiation [62]. This leads to the formation of the pre-metastatic niche (PMN), a ...