Opinion. Discusses the impact of the article `Treatment of the Acute Alcohol Withdrawal State: A Comparison of Four Drugs,' by S.C. Kaim, C.J. Klett and Benjamin Rothfeld on the direction of alcohol research. Original publication in the 1969 issue of the `American Journal of Psychiatry'; ...
Of additional biological interest, the gene regulating the voltage-sensitive calcium channel α2δ-1 protein is upregulated by chronic alcohol exposure and withdrawal.65 Because this is the putative site of gabapentin action,23 this site might be a fruitful target for potential future AUD ...
A pilot open randomized trial of valproate and phenobarbital in the treatment of acute alcohol withdrawal. Am J Addict 1998; 7: 189–97Rosenthal RN, Perkel C, Singh P, et al. A pilot open randomized trial of valproate and phenobarbital in the treatment of acute alcohol withdrawal. Am J ...
If you drink heavily for a long time, you might have problems when you stop or cut back how much alcohol you drink. This is called alcohol withdrawal, and symptoms can range from mild to serious.
Treatment of the acute alcohol withdrawal state: a comparison of four drugs. Treatment of the acute alcohol withdrawal state: A comparison of four drugs. Am J Psychiatry. 1969; 125 :1640–6.Kaim SC, Klett CJ, Rothfeld B. ... SC Kaim,CJ Klett,B Rothfeld - 《American Journal of ...
Dexmedetomidine may offer an advantage over current sedative medications used in the intensive care unit, such as not requiring intubation with its use, and therefore further study is needed to fully elicit its benefit in alcohol withdrawal. Clonidine and dexmedetomidine may provide additional benefit ...
No entry criterion for alcohol withdrawal was used (presumably it was the expectation of withdrawal). Previous studies using a predominantly white male veteran population have demonstrated that only 13% of these subjects required drug treatment.2 Other general hospital studies have revealed that a ...
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This paper reviews recent literature on animal models of and treatment for alcohol abuse under seven categories: agents to block craving or reduce alcohol intake, agents to induce aversion to alcohol, agents to treat acute alcohol withdrawal, agents to treat protracted alcohol withdrawal, agents to ...
OBJECTIVE: To assess the effect of an individualized treatment regimen on the intensity and duration of medication treatment for alcohol withdrawal. DESIGN: A randomized double-blind, controlled trial. SETTING: An inpatient detoxification unit in a Veterans Affairs medical center. PATIENTS: One hundred...