PDB41 INSULIN AND INSULIN ANCILLARY USAGE, THE ANNUAL COST OF TREATING TYPE 2 DIABETES WITH INSULIN IN THE UNITED KINGDOMdoi:10.1016/S1098-3015(10)64989-3FChandlerandPDAmberyandKDeSilvaandSDOSValue in Health
Type 2 diabetes (T2D) typically starts with insulin resistance in peripheral tissues and proceeds with gradual loss of islet function due to the reduction in β-cell mass or dedifferentiation of β cells1,2. More than 30% of T2D patients eventually rely on exogenous insulin treatment. Cadaveric...
Insulin analogues in type 1 diabetes mellitus: getting better all the time. Nat. Rev. Endocrinol. 13, 385–399 (2017). Article CAS PubMed Google Scholar Wu, K. K. & Huan, Y. Streptozotocin‐induced diabetic models in mice and rats. Curr. Protoc. Pharmacol. 40, 5.47.1–5.47.14 (...
The American Diabetes Association recommends metformin as initial oral therapy for T2D, but SGLT2 inhibitors can be considered as add-on therapy if a patient’s A1C goal is not achieved after 3 months. Patient preference must be considered when deciding among SGLT2 inhibitors, sulfonylureas, thiazo...
Preventing type II diabetes and treating impaired glucose tolerance, insulin resistance, hyperlipidemia, atherosclerosis, ischemic injury, and hypercholesterolemia by administering a purine containing a phosphonate group, e.g., N9-neopentyl-2-methylthio-8-(2-(5-phosphono)furanyl)adenine; US 20050277619 ...
In type 2 diabetes, since the insulin does not work correctly, the sugars tend to remain high in the blood, thereby increasing the complications related to this disease. The concept of keto diet revolves around consuming fewer carbs and reducing the spikes in blood sugar after meals. It restri...
Non-insulin pharmacological therapies for treating type 1 diabetes. Expert Opin Pharmacother. (2018) 19:947-60. doi: 10.1080/14656566.2018. 1483339Christian Seerup, Frandsen,Thomas Fremming,etc.Non-insulin pharmacological therapies for treating type 1 diabetes.[J].2018,19(9)....
Effects of insulin resistance and insulin secretion on the efficacy of interventions to retard development of type 2 diabetes mellitus the DA Qing IGT and Diabetes Study 热度: 格列喹酮-Gliquidone Contributes to Improvement of Type 2 Diabetes Mellitus Management ...
Type 2 Diabetes. Type 2 diabetes often occurs in the face of normal, or even elevated levels of insulin. The condition appears to arise from β-cell dysfunction, usually combined with impaired ability of tissues to respond appropriately to insulin (i.e. insulin resistance), which challenges the...
Type 2 diabetes is the most common type of diabetes, which is also known as adult-onset diabetes because it mostly occurs in adults. The disease, caused by a variety of factors, can lead to insufficient insulin secretion in the body or the inability of the human body to effectively use in...