The present invention provides the use of a CNS-penetrant NK-1 receptor antagonist in an oral, once-a-day medicament for the treatment of major depressive disorder, methods of treatment using such a NK-1 receptor antagonist and pharmaceutical compositions comprising it....
A National Institute of Mental Health Statistics shows that about 25% of children and teens between the ages of 13 to 18 have one anxiety disorder or another and up to 6% battle severe anxiety disorder. This disorder may develop in a child as young as three, with symptoms exhibited at age...
Using validated assessments, the researchers measured the severity of symptoms of anxiety across all the disorders using a scale of 1 to 7, with 7 being severe anxiety. Both groups experienced decreased anxiety symptoms, dropping from a mean of about 4.5 for both, which translates to an ...
Patel underwent deep brain stimulation surgery, a rare neurosurgical procedure that can be used for severe obsessive-compulsive disorder, or OCD, when it has been resistant to less invasive treatments.
When anxiety is severe or on going it can start to impact how we function which makes daily tasks become difficult, such as our ability to work, concentrate, sleep, socialising and feeling able to take care of ourselves. What causes anxiety? Sometimes there are clear external stressors that...
Personality disorders (PD) are described as enduring patterns of markedly deviant and pervasive inner experiences and behaviors, with onset in adolescence, which lead to severe distress or impairment. Patients suffering from major depressive disorder (MDD) display higher rates of comorbidity with personal...
These so-called natural emotional responses can persist and become severe. Over time, they can put a strain on your mental – and physical – health. Did You Know? Research suggests that up to 30% of people with heart failure have depression. About 32% have some type of anxiety. Some ...
Bipolar II disorder: In this type of disorder, the patient has at least one episode of depression and at least one episode of hypomania. Hypomania is not a severe form of mania. Cyclothymic Disorder: This is the mildest form of bipolar disorder. The patient experiences mild gloominess/depre...
In addition, children in families receiving the intervention demonstrated fewer severe anxiety symptoms overall, with medium-to-large effect sizes (0.81 at six-months post-intervention, and 0.57 at twelve-month follow-up) (Ginsburg et al., 2015), although these effects diminished somewhat over the...
Anxiety disorders, such as panic disorder, agoraphobia, obsessive-compulsive disorder, social phobia, post-traumatic stress disorder, generalized anxiety disorder, specific phobia, or the like, are treated by administering an effective amount of at least one adenosine A2A receptor antagonist to a patien...