I would have to say if I am honest with myself and those of you reading this, I do not know if we are overtreating prostate cancer. On an individual basis all of us in busy urological practice can point to cases that make us answer this question in different ways. Take the 51-year...
said: "Although survival times are improving, no one with advanced prostate cancer is cured of their disease by hormone therapy alone. These important results move the dial significantly further in terms of what we can do for this large group of men. These...
More than 80% of patients diagnosed with lung cancer, for example, present with metastatic disease. Nanotechnology is not alien to the clinic; more than 40 nanotherapeutics have reached patients, including anticancer drugs and imaging agents. Many current therapies are not reaching the sites of ...
Prostate cancer (PC) is a leading cause of death in older men. Androgen deprivation therapy (ADT) is considered the standard-of-care for men with locally advanced disease. However, continuous androgen ablation is associated with acute and long-term adverse effects and most patients will eventually...
cellular senescence, human cytomegalovirus infection, PI3K-Akt signaling pathway, p53 signaling pathway, measles, kaposi sarcoma-associated herpesvirus infection, Epstein-Barr virus infection, human T-cell leukemia virus 1 infection, IL-17 signaling pathway, prostate cancer, and progesterone-mediated oocyte...
which controls memory and behavior. The former is why you feel a jolt of pleasure after biting into a hamburger. The latter is why your mouth waters whenever you smell someone fire up a grill. Drugs can overload this system, flooding it with dopamine and strengthening the connections that un...
When treating complex cancer pain cases, clinicians should "look outside the box" and consider new agents, as well as new uses and administration routes for older agents.
6. A method of monitoring prostate cancer in a patient for the onset of metastasis comprising: (a) identifying a patient having prostate cancer that is not known to have metastasized; (b) periodically determining levels of CSG in samples of cells, tissues, or bodily fluid from said patient;...
can be treated according to the instant invention include but are not limited to bladder cancer, breast cancer, colon and rectal cancer, endometrial cancer, kidney cancer, leukemia, liver cancer, lung cancer, melanoma, non-Hodgkin lymphoma, pancreatic cancer, prostate cancer, and thyroid cancer. ...
56. The method of claim 1, wherein the castration-resistant prostate cancer is metastatic castration-resistant prostate cancer, and the subject failed a prior therapy comprising an androgen receptor signaling inhibitor or a taxane. 57. 57-63. (canceled) 64. The method of claim 1, wherein fr...