At their behest, I broadened my efforts to seek natural medicines for preventing or treating many human disorders, including cold sores, arthritis, periodontal disease, osteoporosis, cancer, psoriasis, stress, and headaches. My research team and I have now found wonderful natural treatments for many...
15. A pharmaceutical composition for use in the prophylaxis, prevention and/or treatment of infectious periodontal disease caused by bacterial, viral or fungal infection comprising a compound selected from a naturally occurring genetic variant of plasminogen, Lys-plasminogen, Glu-plasminogen, mini-plasmino...
The amino acid sequence of TSG-6 polypeptides for use in the invention may be modified to include non-naturally occurring amino acids or to increase the stability of the compound. When the polypeptides are produced by synthetic means, such amino acids may be introduced during production. The pol...
JP2002538122A|2002-11-12|Methods for increasing bone volume using non-naturally occurring FP selective agonists and bone resorption inhibiting compounds 同族专利: 公开号|公开日 US6455514B2|2002-09-24| EP1117410B1|2005-12-28| US20060183717A1|2006-08-17| US20040110726A1|2004-06-10| DK1117410T...
NF-κB is present in the cytosol of cells, building a complex with its naturally occurring inhibitor IκB. The stimulation of cells, for example by cytokines, leads to the phosphorylation and subsequent proteolytic degradation of IκB. This proteolytic degradation leads to the activation of NF-...
Most naturally occurring proteins and peptides are composed exclusively of the L-isomeric form. D-isomeric amino acids can affect the conformation of a peptide or protein and may lead to increased stability or a change in activity. In some embodiments of the peptide, Leucine is replaced with D...
Similarly, “antibiotic tolerance” refers to the ability of a bacteria to naturally resist being killed by antibiotics and “antifungal tolerance” refers to the ability of a fungi to naturally resist being killed by antibiotics.“Antimicrobial resistance” refers to the ability of a microbe to ...
In some instances, the chromophores are exogenous (i.e., chromophores that are not naturally present in skin or tissue onto which the biophotonic composition as defined herein is to be applied). The present disclosure also provides methods useful for promoting wound healing, in particular of non...
osteogenic proteins that have an amino acid sequence that is homologous to a known osteogenic BMP (e.g., about 80% or more homologous to a known osteogenic protein). Such BMP homologues may be naturally occurring, recombinantly produced, or synthetically produced in whole or in part (see, e...
The carrier material can be any naturally-derived or synthetic material that has suitable solubility in supercritical fluids. For example, biodegradable polymers such as poly(lactic acid), poly(lactic-co-glycolic acid), polycaprolactone have good solubility in SC—CO2 and may be used as the ...