Completed Clinical Trials Groundbreaking research on mesothelioma and lung cancer is not new to Fox Chase. Past studies at the center to improve the standard of care for these cancers include: Cisplatin, Interferon Alfa, Surgery and Radiation Therapy in Treating Patients with Malignant Pleural Mesot...
Clinical Pearls Mesothelioma typically affects elderly patients and symptoms can be slow in development or not recognizable Only about 20% of patients with mesothelioma are good surgical candidates for multimodality treatment It is important to find the disease early, when effective therapies may have a...
Novocure’s commercialized products are approved for the treatment of adult patients with glioblastoma and malignant pleural mesothelioma. Novocure has ongoing clinical trials investigating Tumor Treating Fields in brain metastases, gastric can...
Phase II clinical trials have been completed in mesothelioma, ovarian cancer, NSCLC and pancreatic adenocarcinoma. Phase III trials are underway in pancreatic adenocarcinoma and NSCLC. The FDA has designated the TTFields delivery system as a humanitarian use device for the treatment of pleural ...
OA22.01 STELLAR - interim results of a phase 2 trial of TTFields with chemotherapy for first line treatment of malignant mesothelioma J. Thorac. Oncol., 12 (S329) (2016) Google Scholar [23] T. Voloshin, et al. Alternating electric fields (TTFields) in combination with paclitaxel are therape...
This meta-analysis reported AEs in clinical studies with TTFields torso delivery. Methods 192 patients from 4 pilot studies were included in the analysis: EF-15 (n=41, advanced NSCLC), PANOVA-2 (n=40, advanced pancreatic adenocarcinoma), STELLAR (n=80, malignant pleural mesothelioma) and ...
treatment of newly diagnosed and recurrent GBM. Optune is also in advanced clinical development for multiple additional solid tumor indications. In multiple clinical trials, TTFields demonstrated marked efficacy results and safety profile in NSCLC, pancreatic cancer, malignant mesothelioma and liver cancer....
Commentwww.thelancet.com/oncology Vol 20 December 2019 1623The challenge of improving standard-of-care chemo-therapy with pemetrexed and cisplatin for mesothelioma has proven to be virtually insurmountable since 2004. The addition of novel agents to standard chemotherapy in phase 3 trials has not suc...
In some embodiments, the lung cancer is chosen from small cell lung cancer (SCLC), lung adenocarcinoma, non-small cell lung cancer (NSCLC), bronchioles lung cell carcinoma, and mesothelioma. In some embodiments, the lung cancer is SCLC. In some embodiments, the lung cancer is NSCLC.In some...
Tumor Treating Fields (TTFields) are low-intensity, intermediate frequency, alternating electric fields which are FDA-approved for glioblastoma and malignant pleural mesothelioma. Clinical trials are ongoing for other solid tumor cancers... KK Narasimha,S Michael - Neuro-Oncology 被引量: 0发表: 2020...