Methods of treating diabetic neuropathic pain and post-surgical pain are provided. The methods include administering to an individual a therapeutically effective amount of a compound of Formula I (Compound 1). The method can be used to treat diabetic neuropathy arising from any type of nerve ...
Nerve paincaused by diabetes, known as diabeticperipheral neuropathy, can be severe, constant, and hard to treat. It may start as a tingling feeling, followed by numbness and pain. But there are at least two key points that everyone withdiabetesand peripheral neuropathy should know: Controlling ...
The article discusses the causes and management of neuropathic pain. Some of the causes of neuropathic pain includes the post-herpetic neuralgia, diabetic neuropathy, trigeminal neuralgia and nerve compression. Patients who experience the pain described it as burning, tingling, shooting or like an elec...
5. The method of claim 2, wherein said nerve injury pain is associated with diabetic neuropathy. 6. The method of claim 1, wherein said porphyrin is selected from the group consisting of green porphyrin (hydro-monobenzoporphyrin), hematoporphyrin, and hematoporphyrin derivative. 7. The metho...
Normal wound care is insufficient for diabetic wounds due to the differences in blood composition, vascular development, nerve survival, and inflammatory processes[6,7]. Many therapies have been developed for diabetic wounds in recent years[4,8], but those involving growth factors (GFs) have ...
Efficacy and safety of methylcobalamin, alpha lipoic acid and pregabalin combination versus pregabalin monotherapy in improving pain and nerve conduction v... diabetic neuropathymethylcobalaminpregabalinBackground and Objective: To assess whether methylcobalamin and alpha lipoic acid (ALA) added to pregabalin...
different electrical stimulation methods (bilateral electroacupuncture (BEA), unilateral EA (UEA), transcutaneous electrical acustimulation (TEA, stimulation via surface electrodes placed at acupoints), and sacral nerve stimulation (SNS)) on visceral pain in a rodent model of irritable bowel syndrome (...
Diabetes can cause nerve damage leading to severe pain in the feet, legs and hands, which is known as diabetic peripheral neuropathic pain (DPNP). In the UK, the National Institute for Health and Care Excellence (NICE) recommends amitriptyline, duloxetine, pregabalin or gabapentin as initial ...
. Orally administered available congeners of lidocaine also may be effective, as demonstrated by the analgesic effects of mexiletine in painful diabetic neuropathy Dejgard et al. (1988), supra! and peripheral nerve injury Chabal et al. (1992), supra!, and tocainide in trigeminal neuralgia ...
Epilepsy drug helps ease pain of diabetic condition, study finds; Gabapentin provides patients with another option for treating the symptoms caused when diabetes damages nerve tissue, Mayo doctors say.(NEWS)Burcum, Jill