In this group (n=254), 28 (11%) had severe persistent asthma and their mean age was 44卤SD18 years old. 86% were females. Of these, 57% (n=16) had uncontrolled disease: 35% (n=6) due to non-compliance with treatment; 29% (n=5) pulmonary thrombombolism (scintigraphic ...
Wechsler ME, et al, Bronchial thermoplasty: Long-term safety and effectiveness in patients with severe persistent asthma. J Allergy Clin Immunol, 2013;132:1295-302 19. Castro M, et al, Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: A multicenter, randomized...
After getting Xolair or a placebo for up to five months, "of those who received Xolair, 68% [75 of 110 subjects] were able to eat the single dose of peanut protein without moderate to severe allergic symptoms [e.g., whole body hives, persistent coughing, vomiting], compared to 6% [3...
Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes is a European project investigating mechanisms of severe asthma. Type 2 immunity A type of immunity that provides protection against parasitic infections but is also activated in allergic diseases such as asthma. It is orchestrated by...
Asthma is a chronic airway disease that is mainly treated by inhaled corticosteroids, β2-adrenergic receptor agonists, and leukotriene modifiers. Existing research suggests that responses to anti-asthmatic drugs, such as drug metabolism, lung function, asthma exacerbation, and drug toxicity, are likel...
1). These drugs form a break-through as they offer a solution for specific endotypes of patients with severe and steroid-resistant asthma. However, these biologicals only target effector molecules at the end of the inflammatory cascade and therefore do not have the capacity to cure the disease...
, asthma , and a sinus infection. types of baby cough there are two types of cough that help keep your child’s airways clear: advertisement | page continues below wet cough a wet cough, also called a productive cough, will typically bring up mucus or phlegm, which is a mixture of ...
The aim of NCT02059434, a Two-part Pharmacokinetic and Pharmacodynamic Study of AZD/LAS in Patients With Asthma and COPD, was to assess the safety and tolerability of single doses of AZD/LAS administered by inhalation to patients with mild persistent asthma and moderate to severe COPD and also...
Eosinophilic and Noneosinophilic Asthma: An Expert Consensus Framework to Characterize Phenotypes in a Global Real-Life Severe Asthma Cohort Chest, 160 (2021), pp. 814-830 View PDFView articleView in ScopusGoogle Scholar Holguin et al., 2020 F. Holguin, J.C. Cardet, K.F. Chung, S. Diver...
After getting Xolair or a placebo for up to five months, "of those who received Xolair, 68% [75 of 110 subjects] were able to eat the single dose of peanut protein without moderate to severe allergic symptoms [e.g., whole body hives, persistent coughing, vomiting], compared to 6% [3...