In this group (n = 254), 28 (11%) had severe persistent asthma and their mean age was 44 卤 SD18 years old. 86% were females. Of these, 57% (n = 16) had uncontrolled disease: 35% (n = 6)
Wechsler ME, et al, Bronchial thermoplasty: Long-term safety and effectiveness in patients with severe persistent asthma. J Allergy Clin Immunol, 2013;132:1295-302 19. Castro M, et al, Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: A multicenter, randomized...
Sometimes this phenomenon is referred to as allergic asthma, which means that allergens trigger asthma symptoms such as coughing, wheezing, chest tightness or shortness of breath. An injectable drug called Xolair (omalizumab) is designed to treat moderate to severe persistent allergic asthma....
Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes is a European project investigating mechanisms of severe asthma. Type 2 immunity A type of immunity that provides protection against parasitic infections but is also activated in allergic diseases such as asthma. It is orchestrated by...
After getting Xolair or a placebo for up to five months, "of those who received Xolair, 68% [75 of 110 subjects] were able to eat the single dose of peanut protein without moderate to severe allergic symptoms [e.g., whole body hives, persistent coughing, vomiting], compared to 6% [3...
Asthma is a chronic airway disease that is mainly treated by inhaled corticosteroids, β2-adrenergic receptor agonists, and leukotriene modifiers. Existing research suggests that responses to anti-asthmatic drugs, such as drug metabolism, lung function, asthma exacerbation, and drug toxicity, are likel...
1). These drugs form a break-through as they offer a solution for specific endotypes of patients with severe and steroid-resistant asthma. However, these biologicals only target effector molecules at the end of the inflammatory cascade and therefore do not have the capacity to cure the disease...
, asthma , and a sinus infection. types of baby cough there are two types of cough that help keep your child’s airways clear: advertisement | page continues below wet cough a wet cough, also called a productive cough, will typically bring up mucus or phlegm, which is a mixture of ...
Eosinophilic and Noneosinophilic Asthma: An Expert Consensus Framework to Characterize Phenotypes in a Global Real-Life Severe Asthma Cohort Chest, 160 (2021), pp. 814-830 View PDFView articleView in ScopusGoogle Scholar Holguin et al., 2020 F. Holguin, J.C. Cardet, K.F. Chung, S. Diver...
Addition of long-acting beta2-agonists to inhaled steroids as first line therapy for persistent asthma in steroid-naive adults and children. Cochrane Database Syst Rev. 2009;(4). Google Scholar Sobieraj DM, et al. Association of inhaled corticosteroids and long-acting muscarinic antagonists with...