In recent years a 10 year old girl from 3rd generation, with symptoms since the age of 7y., was brought to medical attention.ResultsShe was undertaken a series of laboratory tests, including gene analysis for FMF and hyper Ig-D syndrome with negative results. 8 years later C73W TRAPS ...
TNF Receptor–Associated Periodic Syndrome (TRAPS) - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the Merck Manuals - Medical Professional Version.
et al. Decreased neutrophil extracellular trap degradation in Shiga toxin-associated haemolytic uraemic syndrome. J. Innate Immun. 9, 12–21 (2017). CAS PubMed Google Scholar Leffler, J. et al. Neutrophil extracellular traps that are not degraded in systemic lupus erythematosus activate complement...
Future treatments might aim to break this cycle to ease RA symptoms. This summary was initially drafted using artificial intelligence, then revised and fact-checked by the author.show all Sections Figures References Abstract Introduction Methods Results Discussion Data availability References Acknowledgements...
SIV, a specific inhibitor of NE, has demonstrated efficacy in the treatment of respiratory diseases, including acute lung injury or acute respiratory distress syndrome with systemic inflammatory response syndrome [20]. Likewise, our results suggested that both SIV and HVO effectively inhibit NETs ...
However, it has been observed that pulmonary surfactant administration is not beneficial in adults with acute lung injury or acute respiratory distress syndrome [128]. Despite the potential benefits of pulmonary surfactants in the treatment of respiratory diseases, their clinical applications still face ...
indicated the interaction between NETs and macrophage pyroptosis, aggravating the inflammation of acute respiratory distress syndrome (ARDS) [60]. The inflammatory microenvironment plays an important role in all stages of tumor development and progression. It is necessary to further understand whether the...
Acute respiratory distress syndrome LDG: Low density granulocyte COVID-19: Coronavirus disease 2019 EDIL3: EGF-like repeats and discoidin I-like domain 3 LFA1: Lymphocyte function-associated antigen 1 ICAM: Intercellular adhesion molecule Mertk−MHC-IIlo−int: ...
respiratory distress syndrome. It has since been used in children with pneumonia, acute lung injury, or acute respiratory distress syndrome. However, it has been observed that pulmonary surfactant administration is not beneficial in adults with acute lung injury or acute respiratory distress syndrome [...
This syndrome is characterized by disrupted protein synthesis, which affects the storage and secretory functions of lysosomal granules in neutrophils and other cells, ultimately resulting in the abnormal fusion of lysosomes with the phagosome46,47. These mutations lead to decreased phagocytosis, defects ...