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The BCS has produced rates and extents by which oral drugs are absorbed. Extended versions of the BCS have been proposed by associating the four classes with the main routes of elimination and the effects of efflux and influx transporters. Their objectives were to predict the pharmacokinetic ...
to Labuan; we have a very good idea as to the number of sorties the aircraft can reasonably be expected to generate. The problem is if the aircraft are suddenly required to maintain a higher tempo indefinitely. Naturally there will be instances when serviceability rates have significantly dropped...
The outcomes demonstrated a significant correlation between increased expression of MPC1, ABCD3, SLC38A4, CLRN3, RETNLB, and ANO7 genes and reduced mortality rates among patients (Fig. 3). These results indicate that the expression levels of these genes, associated with membrane transporters, ...
These findings might sug- gest that the metabolic turnover rates of Glu transporter pro- teins and their corresponding mRNAs are regulated through Acta Pharmacologica Sinica www.chinaphar.com Krzyżanowska W et al npg 449 Table 2. Genes encoding Glu transporter proteins and their chromosomal ...
the degradation rates differ between brain regions. At least some of the observations that there are differences in transporter distributions between human and rodents may be due to the fact that the various antibody epitopes degrade with different rates (for discussion and list of antibody epitopes,...
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since this is a function of the earlier growth rate [156,157], though this typically does not exceed about 8 chromosome contents even at the fastest growth rates [121,158], so variations in DNA content alone could not conceivably explain this range. We therefore also performed growth rate ex...