Translocon-associated protein (TRAP) complex is intimately associated with the ER translocon for the insertion or translocation of newly synthesised proteins in eukaryotic cells. The TRAP complex is comprised of three single-spanning and one multiple-spanning subunits. We have investigated the membrane ...
The translocon-associated protein (TRAP) complex associates with the Sec61 complex and is present in every endoplasmic reticulum (ER) translocon. TRAP has three single membrane-spanning subunits denoted, beta, and delta, while the gamma-subunit spans the membrane four times. TRAP may facilitate ...
Here we show that YfgM, an inner membrane protein with no annotated function, is an ancillary subunit of the Sec translocon. Initially we showed that YfgM and PpiD were physically associated with the translocon when solubilized with digitonin and analyzed by co-immunoprecipitation and two-dimensiona...
Protein Sci: Publ Protein Soc 20(1):179–186. https://doi.org/10.1002/pro.551 Article CAS Google Scholar Bañó-Polo M, Martínez-Garay CA, Grau B, Martínez-Gil L, Mingarro I (2017) Membrane insertion and topology of the translocon-associated protein (TRAP) gamma subunit. Biochim ...