A model for translational science in undergraduate classroomsdoi:10.1002/fee.1920Marja H BakermansGeoff PfeiferWiley-BlackwellFrontiers in Ecology & the Environment
Clinical and translational science is the term for multidisciplinary, team-based research that has the goal of transforming basic science discoveries to improve human health through new diagnostic techniques, new therapies, advances in clinical practice and new community-based interventions or population he...
Open-source computational solutions currently available for translational science does not have a model to represent biomolecular information and also are not integrated with the existing bioinformatics tools. On the other hand, existing genomic data models do not represent clinical patient data. A framew...
states. Together, all these aspects of cancer research have contributed to reduce the time from the discovery of a new basic science concept to the clinical proof of concept, and subsequently to the application of a safe and effective new therapy in clinical practice. Thus, the US Food and ...
Translating the knowledge from biomedical science into clinical applications that help patients has been compared to crossing a valley of death because of the many issues that separate the bench from the bedside and threaten to stall progress. But transl
Our deep learning model was cross-validated on the ADNI-1 and ADNI-2/GO cohorts and further generalized in the ongoing ADNI-3 cohort. We evaluated the model performance using the area under the receiver operating characteristic curve (AUC), accuracy, sensitivity, specificity, and F1 score. ...
in addition to effects on core dimensions of mental health (e.g., anxiety, mood, cognition, and motivation), musical treatments have also been found efficacious in more specific cases of psychopathology that specifically feature reward dysfunction. Some examples include: substance-use disorder, where...
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Evolutionary innovations can be driven by changes in the rates of RNA translation and the emergence of new genes and small open reading frames (sORFs). In this study, we characterized the transcriptional and translational landscape of the hearts of four
examples of this phenomenon, including both static and dynamic stimuli. Static versions include the Necker cube and Rubin’s face-vase illusions, while dynamic versions include the spinning dancer, point light walker, and the rolling wheel. There are both static and dynamic examples of binocular ...