This section aims to provide a platform for the interaction and mutual validation between basic and applied research in the field of nutrition. In the area of Translational Medicine, we believe that the field ought to be taken into greater account in ...
The observed AAs profile disturbances in both AF and aging suggest that AAs may participate in the development of age-related AF. However, AA alterations in age-related AF have not been investigated. To address this gap, our study analyzed plasma AA levels of persistent AF patients and their ...
DNA methylation (DNAm) is a key biomarker of aging, with age-related DNAm changes being well-characterized. Here, the authors show that low-methylated regions (LMRs) bound by PRC2 in embryonic stem cells gain methylation with age in somatic cells, proposing the “PRC2-AgeIndex” as a un...
therapeutics and education for all aspects of neurodegenerative diseases. By offering a high-visibility forum for new insights and discussions, Translational Neurodegeneration creates a novel interface between the fields of basic, translational, and clinical research. It includes Parkinson's disease and...
Frailty is a multiply determined, age-related state of increased risk for adverse health outcomes. We review how the degree of frailty conditions the development of late-life diseases and modifies their expression. The risks for frailty range from subcel
of metastatic cancer cell markers in blood, Personalized and Precision Medicine & Genomic Research, Precision Cancer Medicine, REAL TIME Conference Coverage Twitter's Hashtags and Handles per Presentation/session, Simulation Modeling in NGS, tagged Advancing Precisio...
Retinoblastoma, an intraocular pediatric cancer, develops in the embryonic retina following biallelic loss of RB1. However, there is a wide range of genetic and epigenetic changes that can affect RB1 resulting in different clinical outcomes. In addition,
2022, Journal of Translational Medicine RNA-binding proteins and their role in kidney disease 2022, Nature Reviews Nephrology Tau oligomers mediate aggregation of RNA-binding proteins Musashi1 and Musashi2 inducing Lamin alteration 2019, Aging Cell Musashi-1 Enhances Glioblastoma Cell Migration and Cytosk...
Excessive energy intake in modern society has led to an epidemic surge in metabolic diseases, such as obesity and type 2 diabetes, posing profound threats to women’s reproductive health. However, the precise impact and underlying pathogenesis of energy
Gene signatures, immune infiltration, and drug sensitivity based on a comprehensive analysis of m6a RNA methylation regulators in cervical cancer Xiaoqin Lu, Rui Li, Yanqi Ying, Wenyi Zhang & Wuliang Wang Journal of Translational Medicine volume 20, Article number: 385 (2022) Cite this article ...