4.BiologyThe process by which messenger RNA directs the amino acid sequence of a growing polypeptide during protein synthesis. trans′la·to′ry(-lə-tôr′ē)adj. American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing...
Protein translation, one of the most fundamental and exquisitely controlled processes in biology, has received little attention inPD. Protein translation is the overall process whereby proteins are synthesized from thegeneticinformation ofRNAtranscripts (Figure 1). This process is divided into thr...
This paper introduces a new model of computation that employs the tools of molecular biology whose in vitro implementation is far more error-resistant than... M Amos,A Gibbons,D Hodgson - University of Warwick 被引量: 144发表: 1998年 Suppression of DNA synthesis and induction of apoptosis in...
Paul D.Ray,Rebecca C.Fry, inSystems Biology in Toxicology and Environmental Health, 2015 Decoding the Genome (II): Translation The process of deciphering the DNA code into proteins, which will carry out the myriad functions of the cell, is a multistep process. Transcription “reads” the DNA...
Nature Reviews Molecular Cell Biology volume 19, pages 791–807 (2018)Cite this article 16k Accesses 38 Altmetric Metrics details Abstract Advances in sequencing and high-throughput techniques have provided an unprecedented opportunity to interrogate human diseases on a genome-wide scale. The list of ...
Department of Cell and Molecular Biology, Uppsala University, 75236, Uppsala, Sweden Arvid Hedén Gynnå Contributions S.Y., A.H.G. and N.K.L. designed the experiments; S.Y., S.K. and N.K.L. wrote the manuscript; S.Y. performed the microscopy experiments. S.Y. and S.K. perfor...
Consistent with the views of the vast majority of the PGS research community, the ACMG’s statement advocates against using PGS as a standalone test, as a negative result is not conclusive, and a positive result does not always mean the carrier is at high immediate risk. As we have highlig...
The end result is a set of log-likelihood weights for ATG/GTG/TTG information and for each of the above RBS bins. If the zero bin for RBS motifs, which corresponds to no SD motif, is positive, or if the zero bin is above -0.5 and the 4-base motif bins are less than 1.0, then...
mRNA translation on the spindle is hypothesized to be an essential strategy for the localized production of cell regulators. This mechanism may be important particularly in early embryonic cells, which have a large diffusion volume and that undergo rapid
This work was supported by the National Institutes of Health Director’s Early Independence Award (DP5-OD-024590), the NASA Exobiology Program (NNH17ZDA001N-EXO), and the Broad Institute of MIT and Harvard. We additionally thank the laboratories of Deborah Hung, Paul Blainey, Scott Manalis,...