This review does not intend to be a full-coverage of the literature but rather to reflect the lively discussion that took place on the EuroTau meeting 2018, in Lille, France. Aggregate structure: From heparin-induced structure to native conformation The characterization of amyloid structures is ...
To grasp the molecular characteristics of tau structures is challenging. First of all, as a large IDP, tau is flexible and dynamic and requires high-field nuclear magnetic resonance spectroscopy (NMR) to collect molecular detail. Tau has a low complexity amino-acid sequence, and recently joined ...