Predictors of the response to treatment in anemic hemodialysis patients with high serum ferritin and low transferrin saturation. Kidney Int. 2007;71(11):1163-71.http://dx.doi. org/10.1038/sj.ki.5002223 ; PMid:17396118.Singh AK, Coyne DW, Shapiro W, et al. Predictors of the response to ...
saturation of transferrin with iron is calculated by dividing the serum iron concentration by the TIBC and multiplying by 100. Serum TIBC is low-normal or decreased in association with inflammatory disorders (Feldmanet al., 1981b;Ottenjannet al., 2006;Smith and Cipriano, 1987) and increased in...
After a 6-week treatment with an anti-transferrin antibody, a decrease in transferrin plasma concentration was observed (Supplementary information, Fig.S10a). This was accompanied by a relative decrease in the enzymatic activities of thrombin (Supplementary information, Fig.S10b) and FXIIa (Supplemen...
Effect of low and moderate doses of recombinant human erythropoietin on the haematological response in premature infants on a high protein and iron intake saturation indicated no iron deficiency, soluble transferrin receptor increased in both groups, more rapidly and to higher levels in the 100 IU/...
Few data exist to guide treatment of anemic hemodialysis patients with high ferritin and low transferrin saturation (TSAT). The Dialysis Patients' Response to IV Iron with Elevated Ferritin (DRIVE) trial was designed to evaluate the efficacy of intravenous ferric gluconate in s...
Method Ferritin, transferrin, iron, transferrin saturation (TSAT) and hepcidin were measured in baseline, pre-treatment, serum samples from 202 randomly selected patients with severe alcoholic hepatitis (AH) recruited prospectively via the STOPAH trial. Hepatic transferrin mRNA expression was assessed ...
The observation group was treated with high-flux hemodialysis, while the control group was treated with low-flux hemodialysis for 6 months. Compare two groups before and after treatment serum beta 2 microglobulin (beta 2 - MG), serum creatinine (Scr), blood urea nitrogen (BUN) level, anemia ...
In animals exposed to hyperoxia, treatment with iron-free TF decreased malondialdehyde content of BAL. We propose that low iron saturation of TF decreases oxidant stress and favors the recovery from respiratory failure. Pediatr Pulmonol. 1996;22:14鈥 22. 1996 Wiley-Liss, Inc....
These patients have either normal or high serum ferritin levels, but present a frankly decreased transferrin saturation. It is therefore of paramount importance to screen functional iron deficiency—which usually responds to iron therapy—from the so-called inflammatory iron block, which is insensible ...
In addition to the density of TRs on the tumor cell surface, the efficacy of Tf-toxin conjugate is influenced both by the Tf-iron saturation state and by the presence of free diferric Tf in the tumor microenvironment. The affinity of Tf-Saporin (Tf-SO6) to TR was greatly diminished whe...