Transferrin saturation is a calculated value resulting from a medical laboratory test to measure the amount of iron bound to transferrin in the blood. The liver produces transferrin, which is a protein that serves to bind iron molecules and carry them through the bloodstream to the bone marrow. ...
Transferrin is an iron-transporting glycoprotein found in the blood. When the protein is not bound with iron, it is called apotransferrin and will not bind with a transferrin receptor at physiological pH. Once iron is bound, however, apotransferrin will undergo a conformation change that will ...
low free iron concentration limits oxygen free radical generation and protects againstthe spread of iron-dependent bacteria in the blood and tissues. Even a minor increase, typical for individuals with heterozygous variants of the hemochromatosis geneHFE, raises the risk of deadly sepsis (Gerhard et ...
The role of transferrin in promoting hypercoagulability was further investigated in a mouse thrombosis model induced by FeCl3. As illustrated in Fig.5g, blood flow in the carotid artery was significantly decreased in transferrin-overexpressed mice, suggesting an increased thrombus formation. Inversely, ...
Levels of serum iron, total iron binding capacity, transferrin saturation fraction and packed cell volume of blood donors in Calabar, Cross River State, Nigeria. Pakistan J Nutri 2008; 7: 500-2.Akpotuzor JO, Isong C. Okpokam DC, Etukudo MH. Levels of serum iron, total iron binding ...
Presents an abstract of a study which evaluates the effect of blood transfusion on serum iron and transferrin saturation. Design; Patients; Results and conclusions.SaxenaSunitaSmithJeanetteM.JAMA: Journal of the American Medical AssociationSaxena S, Shulman IA, Johnson C. Effect of blood transfusion ...
blood has a significant negative correlation with that of the percentage saturation of plasma transferrin of the sample.The maternal percentage saturation of plasma transferrin has a significant positive correlation with that of the corresponding fetal (cord) sample.There was no significant correlation ...
Only 8 patients could be diagnosed as having IDA by means of routine blood test results (serum iron, ferritin, and transferrin saturation levels). In contrast, the TR-F index disclosed IDA in 43 of the 49 patients, thus increasing the sensitivity from 16% to 88%. The diagnosis of IDA ...
Blood alcohol level CDT Carbohydrate-deficient transferrin CAGE Cut down, Annoyed, Guilty, Eye-openner DSM-IV Diagnostic and Statistical Manual of Mental Disorders, Version 4 gGGT Gamma glutamyl transferase MAST Michigan Alcoholism Screening Test ...
Transferrin is present in the blood in different iron-bound forms: devoid of iron (apotransferrin, ATf), as monoferric Tf, or as diferric Tf (holotransferrin, HTf). The relative amount of iron-free and iron-loaded Tf in blood is given in terms of the % Tf saturation (TSAT), an ...