However, as these loci contain exclusively structural genes, lacking the portal, terminase, and other GTA-associated genes, more loci are expected to be associated with BhGTA. Candidate BhGTA genes at multiple locations have been predicted due to the presence of a putative regulatory hexanucleotide...
Negative controls in which the primary antibody was omitted were included for each staining. Live cell recording, confocal imaging and scanning electron microscopy (SEM) SH-SY5Y cells stably expressing α-syn-EGFP, α-syn-A53T-EGFP, α-syn-mCherry, or mCherry were used to study exchange ...
Gene-specific selective sweeps in bacteria and archaea caused by negative frequency-dependent selection. BMC Biol. 13, 1–11 (2015). The authors show that in the presence of NFDS, genes or mutations that are unconditionally beneficial can spread through populations only via HGT, giving rise to ...
Effects of a Conditional Cash Transfer Program on Children's Behavior Problems OBJECTIVES: Governments are increasingly using conditional cash transfer programs to reduce the negative effects of poverty on children's development. Thes... EJ Ozer,LCH Fernald,JG Manley,... - 《Pediatrics》 被引量:...
Domain-independent feature representation in transfer learning can also have significant effects on performance (e.g., to avoid negative transfer) [8]. Spectral techniques have been used to ad- dress the problem of combined feature representation [2]. How- ever, such spectral techniques (e.g.,...
1b). Zeta-potential detection showed that Cit- and PEG-GNPs had negative surface charge; however, PEG-GNPs had much less negative charge than non-PEGylated particles. The CS-GNPs and PEI-GNPs both had positive surface charge (Fig. 1b). The FTIR and XPS spectra showed that the PEG, CS...
fluidity of actors and ties may involve high levels of sunk costs and loss of knowledge of discontinuing actors. Hence, it is unclear if a high level of fluidity has a positive or negative effect on system performance.Footnote29To what extent is the knowledge of discontinuing actors lost for ...
The experience of radiation accidents, the Chernobyl accident in the first place, has shown that the methodology used to develop and estimate the effectiveness of countermeasures to reduce negative consequences of accidental contaminatio... AV Konoplev,AA Bulgakov,VE Popov,... - Springer Netherlands...
Negative control, APCs with unlabelled telomeres. (e) Immunofluorescence staining of POT1 and telomere TelC PNA probe live delivery on primary human APCs (CD3-depleted PBMCs). POT1 recruitment to telomeres was detected directly ex vivo. Scale bar, 10 µm. (f) Manders co-localization ...
Besides performing mosaic integration on the latent space (see ‘Mosaic integration on latent space’), we can also perform it on the feature space, that is, imputing missing values and correcting batch effects for the count data. Mosaic integration on feature space is important because it is ...