The transducin-like enhancer of split-1 (TLE1) is a transcriptional corepressor whose functions in macrophages have not been studied yet. We report that TLE1 is highly expressed in human alternative macrophages in vitro and in atherosclerotic plaques as well as in adipose tissue M1/M2 mixed ...
The Drosophila Groucho protein and its mammalian orthologues the transducin-like enhancers of split (TLEs) are critical transcriptional corepressors that repress Wnt and other signaling pathways. Although it is known that Groucho/TLEs are recruited to target genes by pathway-specific transcription factor...
世联博研公司现货供应abbexa品牌订货号为Catalogue No: abx145023的Transducin Like Enhancer of Split 2 (TLE2) Antibody产品
MBS714583 | Rabbit anti human transducin like enhancer of split 1(E(sp1)同系物,果蝇)多克隆抗体[分裂1的转基因增强剂]大小:NA |;请询问 MBS711695 |;分裂3的兔抗人转基因增强剂(E(sp1)同系物,果蝇)多克隆抗体大小:0,05 mL | MBS711695 |;分裂3的兔抗人转基因增强剂(E(sp1)同系物,果蝇)多克隆抗体...
Here we demonstrate that the human ARX protein is a potent transcriptional repressor, which binds to Groucho/transducin-like enhancer of split (TLE) co-factor proteins and the TLE1 in particular through its octapeptide (Engrailed homology repressor domain (eh-1) homology) domain. We show that ...
Transgenic overexpression of adipose tissue (AT) transducin-like enhancer of split 3 (TLE3) mimicked peroxisome proliferator-activated receptor gamma (PPARγ) agonists, improving insulin resistance in mice. This study aimed to investigate TLE3 gene expression (qRT-PCR) and protein (Western blot) in...
Stifani, "Transducin-like enhancer of split 2, a mammalian homologue of Drosophila Groucho, acts as a transcriptional repressor, interacts with hairy/enhancer of split proteins, and is expressed during neu- ronal development," European Journal of Biochemistry, vol. 258, no. 2, pp. 339-349, ...
Transducin-like enhancer of split 1 (TLE1) belongs to the Groucho/TLE family, and it functions in the "off" state in the Wnt/尾-catenin signaling pathway. We hypothesized that if the dysregulation of the Wnt/尾-catenin signaling pathway could be attributed to the tumorigenesis of BCA/BCAC...
Sirt1 interacts with transducin-like enhancer of split-1 to inhibit nuclear factor kappaB- mediated transcription. Biochem J 2007;408:105-111Ghosh HS,et al.Sirt1 interacts with transducin-like enhancer of split-1 to inhibit nuclear factor kappaB-mediated transcription. Biochemical Journal . 2007...
The present invention relates to nucleotide sequences of the human transducin-like (Enhancer of split) ( TLE ) genes, and amino acid sequences of their encoded TLE proteins. The invention further relates to fragments and other derivatives, and analogs, of human TLE proteins, as well as ...