BRIE: transcriptome-wide splicing quantification in single cells. Genome Biol. 2017;18:123. https://doi.org/10.1186/s13059-017-1248-5.Huang Y, Sanguinetti G (2017) Brie: transcriptome-wide splicing quantification in single cells. Genome Biol 18(1):123...
Overview of future research direction of TWAS in CD. GWAS, genome-wide association studies; TWAS, transcriptome-wide association studies; eQTL, expression quantitative trait loci Full size image Epidemiologic studies have reported that the incidence of IBD has now leveled off in developed areas but c...
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et al. Transcriptome-wide profiling identifies colon cancer-associated m6A transcripts and potential RNA methyl modifiers. Mol Biol Rep 51, 299 (2024). https://doi.org/10.1007/s11033-024-09217-x Download citation Received27 October 2023 Accepted05 January 2024 Published12 February 2024 DOIhttps:/...
Functional genomic methods are needed that consider multiple genetically correlated traits. Here we develop and validate Transcriptome-wide Structural Equation Modeling (T-SEM), a multivariate method for studying the effects of tissue-specific gene expre
Discovery of interaction sites between RNA-binding proteins (RBPs) and their RNA targets plays a critical role in enabling our understanding of how these RBPs control RNA processing and regulation. Cross-linking and immunoprecipitation (CLIP) provides a generalizable, transcriptome-wide method by which...
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These 2,938 transcripts do not include transcripts that showed stable, non-changing expression levels. While the entire analysis was performed at the transcriptome-wide level, detailed mining of splicing events and function predictions was only performed on the smaller data set of 2,938 transcripts....
Rice bean (Vigna umbellata), an underrated legume, adapts to diverse climatic conditions with the potential to support food and nutritional security worldwide. It is used as a vegetable, minor food crop and a fodder crop, being a rich source of proteins,
we analyze the transcriptome-wide distribution of m6A in HeLa and mouse embryonic stem cells. The enzymatic deamination route employed by eTAM-seq preserves RNA integrity, facilitating m6A detection from limited input samples. In addition to transcriptome-wide m6A profiling, we demonstrate site-specific...