Transcription start site (TSS): Site where DNA transcription begins. From:Seminars in Immunology,2016 About this page Set alert Chapters and Articles You might find these chapters and articles relevant to this topic. Epigenetics and Cancer, Part B ...
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rates as WT cells (Fig.4c). Mutations in the ATPase-binding domain and ubiquitin-binding domain (UBD) of CSB showed that both domains were equally important after UV-induced and FA-induced damage (Fig.4dand Extended Data Fig.5e,f), which suggests that CSB performs a similar function during...
is thought to occupy the channel that will hold the DNA downstream of the transcription start site; thus, region 1.1 must move from this channel as RP... IG Hook-Barnard,DM Hinton - 《Proceedings of the National Academy of Sciences of the United States of America》 被引量: 55发表: 2009...
Each transcription factor binds preferentially to a consensus sequence, or motif, usually located just upstream of the transcription start site—in other words, the promoter region. If a polymorphism disrupts that motif, the transcription factor may be less able to bind to the promoter and ...
A set of loss-of-function assays led to the identification of three CO₂-responsive elements, TGACGT, ACGTCA, and TGACGC, at a region –86 to –42 relative to the transcription start site. Treatment with a cyclic (c) AMP analog, dibutyryl cAMP, revealed these three elements to be ...
Just submit a FASTA file of your species of interest to start the analysis. #MybMonday (https://doi.org/10.1186/s12864-022-08452-5) The automatic MYB annotation workflow (Pucker, 2022) is now available as an online service: MYB_annotator online. Users can submit a FASTA file with ...
The promoter region of the NPY gene consists of TATA and GC boxes which are separated from the transcription start site (TSS) by 29 and ~100 nt, respectively. Analyses of the tissue specific expression of the bovine NPY gene revealed the presence of highly abundant NPY gene transcripts in ...
(2 kb upstream from the transcription start site), gene body, 3′ untranslated region (2 kb downstream from the translation termination site), and intergenic region. Of these SlDof1 binding sites, 22.4% were located in promoter regions (Fig.4D). Detailed analysis of the SlDof1 binding...
start codon of protein-coding genes were classified as (i) TSS of mRNAs (mTSS). 54 nt were defined as the minimal region upstream of the ATG to cover promoter motifs and the ribosome binding site, which are more likely to be associated with an mRNA than to atrans-encoded sRNA. (ii) ...