What enzymes/proteins involved in the process of unwinding DNA? What is the proofreading mechanism of DNA, and which enzymes are involved? What is transcription? Why is it necessary? Where in the cell does it o
transcription (RT–qPCR) in introns throughout the gene body of specific long genes (Extended Data Fig.1l). Directly after Pol II promoter release by flavopiridol washout, nascent transcription was primarily detected at the beginning of genes. These transcription levels were not affected after FA e...
Where in the cell does transcription take place? Which region of transcription has premotor? What is accomplished in the process of transcription? What is being copied, and what form does the copy take? What does the transcription of cells mean in cellular biology?
Pluripotent stem cells provide a powerful system to dissect the underlying molecular dynamics that regulate cell fate changes during mammalian development. Here we report the integrative analysis of genome-wide binding data for 38 transcription factors w
When a cell needs to make a new protein, it copies the DNA into a new molecule of mRNA. The DNA is then free to float in the cytoplasm until it is needed again. Transcription happens in the cytoplasm of the prokaryote, where a single long strand of DNA resides. DNA is made up of ...
We first assessed GET’s ability to accurately predict gene expression in unseen cell types in a setting where one cell type is left out during the expression fine-tuning process. On left-out astrocytes and genes with accessible promoters, the Pearson correlation between GET’s predicted expression...
Visualize how mRNA splicing happens by watching the process in action in this video. See how introns are removed during RNA splicing here. Think about It In eukaryotic cells, how is the RNA transcript from a gene for a protein modified after it is transcribed?
Initiation of transcription happens when the compact DNA structure is loosened and short sequence elements in the 5′ end of the gene guide and activate RNA polymerase (Figure 5-6). A group of such sequences is often clustered upstream of the transcription initiation site to form the promoter...
bZIP transcription factors PcYap1 and PcRsmA respond to the presence of H2O2-generated ROS and regulate oxidative stress response in the cell. Both proteins mediate ROS regulation of penicillin biosynthesis and conidiation by binding to specific regulatory elements in the promoters of key genes. PcYa...
Transcription happens (in the nucleus/out of the nucleus). What does transcription produce? Where is DNA located in a cell? How does transcription occur, and what are its steps and directionality? Where in a cell would you find DNA? What is transcription? Why is it necessary? Where in the...