ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation Mette Bentsen Philipp Goymann Mario Looso Nature Communications(2020) Nature Communications (Nat Commun)ISSN2041-1723(online) Sign up for theNature Briefingnewsletter — what matters in science, free ...
Two main molecular mechanisms and signaling pathways of the resilience pathways are the heat shock factor (HSF) and Kelch-like ECH-associated protein 1 (Keap1)-nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element (ARE). Keap1-Nrf2/ARE is the major signaling pathway ...
Another patterning reverse was found in transcription factor AP-2α (Tfap2a) optic vesicle mutants leading to replacement of the RPE by neural retinal and optic stalk-like tissue (Bassett et al., 2010). These are significant findings that pave the road for additional studies of genes and ...
transactivation activity at thePGFpromoter, among others [99]. These findings provide an example of how an interaction between TFs impacts their activity and outcome. The transcription factor activator protein-2 alpha (AP-2α; TFAP2A) was reported as a critical regulator of biochemical but not m...
aStructure of the known pioneer transcription factor FoxA (PDB:5X07 [https://www.rcsb.org/structure/5X07]), and LFY monomer (top right) or dimer (bottom) (PDB:2VY1) bound to DNA. Red: All base contacting residues, including the DNA anchoring helix. Arrows delineate the DNA region cont...
Using a yeast one hybrid screen with the Ret1 cis-element (GCCAATTAA) as bait and a Xenopus laevis adult retina cDNA library, we identified a novel gene, which we name Rax2b (Accession number: JN392465). Rax2b is a member of the Rax paired-like homeodomain transcription factor family ...
The CcMYB24 showed a higher expression level in 'TRIR-2' than in control plants, and the protein was located in the nucleus. The sequence of CcMYB24 showed a high similarity with RAX2-like genes which belong to the R2R3-MYB gene family in other Cymbidium plants. Over...
DifferentialregulationofcloselyrelatedR2R3-MYB transcriptionfactorscontrolsflavonolaccumulation indifferentpartsoftheArabidopsisthalianaseedling RalfStracke 1 ,HirofumiIshihara 1,2 ,GunnarHuep 1 ,AikoBarsch 2,3 ,FrankMehrtens 1 ,KarstenNiehaus 3 andBerndWeisshaar 1, * 1 DepartmentofBiology,GenomeResearch,Bi...
Genome-wide exploration of the CONSTANS-like (COL) gene family and its potential role in regulating plant flowering time in foxtail millet (Setaria italica) Article Open access 18 October 2024 Introduction WUSCHEL-related homeobox (WOX) gene family are plant-specific transcription factors, which bel...
Several of the TFs lack orthologues in mouse (ARGFX, CPHX1, CPHX2, DPRX, LEUTX, RAX2 and TPRXL) and many of them are activated in the zygotes or the later stages, suggesting novel primate-specific functions in early development23. PRD-like homeobox genes—novel regulators of EGA. ...