2003. Cell cycle regulation by the B-Myb transcription factor. Cell. Mol. Life Sci. 60: 2389- 2401.Joaquin, M., and Watson, R.J. (2003). Cell cycle regulation by the B-Myb transcription factor. Cell. Mol. Life Sci. 60, 2389-2401....
The transcription factor Aire mediates tissue-specific antigen expression in the thymus for T cell central tolerance induction. Here the authors show that Aire, via its CARD domain, forms multimers that can misdirect Aire to PML bodies leading to the loss of Aire transcriptional activity and induct...
Altering the positive limb core molecular clock transcription factor, CLOCK, or CLOCK-output genes, accelerates visual senescence, induces a systemic immune response, and shortens lifespan. Flies subjected to dietary restriction are protected from the lifespan-shortening effects of photoreceptor activation...
Maintaining quiescent cells in G0 phase is achieved in part through the multiprotein subunit complex known as DREAM, and in human cell lines the transcription factor E2F4 directs this complex to its cell cycle targets. We found that E2F4 binds a highly overlapping set of human genes among thr...
As a cellular metabolic and stress sensor, thetranscription factor Nrf2is a pivotal regulator of stem cell self-renewal, proliferation, and differentiation. Nrf2 displays cell type-specific and/or stage-dependent impact on stem cell biology in response to various environmental cues. ...
MCE 转录因子化合物库 Transcription Factor Targeted Library.docx,信号通路化合物库系列 According to Signaling Pathway or Protein Family 细胞转导是一个复杂的网络系统,包括细胞-细胞间的相互作用及细胞内的信号转导。胞外信号分子经受体介导进入胞内的信号转导是最
TakehitoInaba, ...KatsuhiroNakayama, inInternational Review of Cell and Molecular Biology, 2011 8.3Other transcription factors Transcription factors that exhibit dual localization in bothplastidand nucleus are of great interest in the study of plastid signaling. Atranscription factor IIB-related pr...
Inferring yeast cell cycle regulators and interactions using transcription factor activities Since transcription factors are often regulated at the post-transcriptional level, their activities, rather than expression levels may provide valuable inf... YL Yang,J Suen,MP Brynildsen,... - 《Bmc Genomics》...
Transcription factor, molecule that controls the activity of a gene by determining whether the gene’s DNA is transcribed into RNA. Transcription factors control when, where, and how efficiently RNA polymerases, which catalyze the reactions that synthesi
Pluripotent stem cells provide a powerful system to dissect the underlying molecular dynamics that regulate cell fate changes during mammalian development. Here we report the integrative analysis of genome-wide binding data for 38 transcription factors w