Nature Cell Biology volume 26, pages 797–810 (2024)Cite this article 15k Accesses 12 Citations 89 Altmetric Metrics details Abstract Covalent DNA–protein cross-links (DPCs) are toxic DNA lesions that block replication and require repair by multiple pathways. Whether transcription blockage ...
A transcription initiation site is the location on a DNA molecule where the process of transcription begins. It determines the structure of the 5'-UTR and can contain features that inhibit translation. AI generated definition based on: Mechanisms of Development, 2001 ...
aVenn diagram showing the overlap of up-regulated transcriptional factors in gland (referred to Supplementary Fig.1), down-regulated genes inpMTR1: GCR1and up-regulated genes incr-gcr1/2.bThe relative expression level ofLFSandHD9inpMTR1: GCR1andcr-gcr1/2based on the transcriptome data.cLUC ...
To visualize the landscape of transcription factors at the genome-wide level, we have constructed a CIRCOS diagram (Fig.3A). From the results, a total of 1134 TFs (Supplementary Table S2) were distributed in 32 normal chromosomes and 2 sex chromosomes (Z and W), where 41 TFs were located...
Although this problem is known based on previous work in virology, it is often ignored in cell biology research dealing with gene expression. Instead, the concern is mostly focused on discrimination against genomic DNA contamination and/or carry-over DNA, which can give a false-positive PCR ...
Schematic diagram of intron distribution patterns within the MYB domains of soybean MYB (GmMYB) proteins.Alignment of MYB domains is representative of 14 intron patterns, designated a to n. Locations of introns are indicated by white triangles, and the number within each triangle indicates the spli...
Mock IgG, hnRNPK, and XRN2 immunoprecipitates were reduced, alkylated, digested with trypsin, and subjected to MS analyses The Venn diagram depicts a number of proteins identified in IP reactions using anti-hnRNPK and anti-XRN2 antibody. B, a protein interaction network constructed with STRING ...
coli, and this dCas9-ω complex increased the reporter gene transcriptional level up to 2.8-fold [37]. The models of CRISPR mediated transcriptional regulation are shown in Figure 2. Figure 2. The diagram of CRISPR/dCas9-mediated transcriptional regulation. The dCas9 fused with transcriptional ...
Users can select any of the proteins from the pathway diagram of curated or a projected pathway to see associated data on genes and proteins; visualize tissue-specific expression of specific gene projected from the EMBL-EBI Gene Expression Atlas [142]; and upload their data for analysis and ...
Ch 18.Campbell Biology Chapter 18: Regulation of Gene... Induction & Repression in Gene Expression8:17 Lac Operon Function, Diagram & Regulation9:25 Differential Gene Expression | Definition & Analysis6:19 Chromatin Structure, Location & Examples4:45 ...