( 1983 ). Specific transcription and RNA splicing defects in five cloned β -thalassaemia genes . Nature 302 , 591 – 596 .Treisman, R., S. H. Orkin, and T. Maniatis. 1983. Specific transcription and RNA splicing defects in five cloned beta-thalassaemic genes . Nature (Lond.) . 302 ...
The disrupted RNA processes increase the FS transcripts generated by RNA splicing errors and the insertions and deletions (INDELs) of MSs22. Both of these processes, combined with the disrupted quality control system in tumor cells, can lead to the production of FS peptides and exposure of the...
▸RNA splicing = processing the RNA to remove regions that will not be included in the final protein; ▸Export = preparing the processed RNA to be moved into the cytosol and translated into protein; ▸Translation = building of a protein according to the sequence of the messenger RNA; ...
protein–protein interaction isothermal titration calorimetry (ITC) RNA splicing protein structure RNA-binding protein protein domain gene regulation Introduction Tat stimulatory factor 1 (Tat-SF1)4 was originally identified as a host cofactor that activates Tat-directed HIV-1 transcription (1, 2). Sub...
55、的催化的RNARNA合成合成3.2 RNA3.2 RNA聚合酶聚合酶I I识别的启动子识别的启动子3.3 Pol3.3 Pol识别的启动子识别的启动子3.4 RNA3.4 RNA加工加工(1) Capping (5 端加帽)端加帽)(2) Polyadenylation (3 端多聚腺苷酸化)端多聚腺苷酸化)(3) RNA splicing (RNA 剪接剪接)(4) Editing (RNA编辑)编辑...
mRNA capping, pause release, splicing, and termination have been visualized. This review will focus on the structural basis of elongation, emphasizing recent structures of paused, paused released, and activated elongation complexes. We also review structures of co-transcriptional processes and termination...
- Rna 被引量: 715发表: 2004年 Higher level organization of individual gene transcription and RNA splicing Visualization of fibronectin and neurotensin messenger RNAs within mammalian interphase nuclei was achieved by fluorescence hybridization with genomic, com... Y Xing,C Johnson,P Dobner,... - ...
Based on this approach, our data suggest that transcription and splicing not only regulate gene expression, but also carry out combinational regulation of the balance between survival and apoptosis of HUVECs under mimicked hypoxia conditions. Since cell survival following the apoptotic challenge is ...
Transcription, the synthesis of RNA from DNA. Genetic information flows from DNA into protein, the substance that gives an organism its form. This flow of information occurs through the sequential processes of transcription (DNA to RNA) and translation (
cells. transcription is carried out by the enzyme rna polymerase. rna polymerase uses the antisense strand of dna as a template to make mrna. pre-mrna is unprocessed and can be post-transcriptionally modified by processes such as polyadenylation and rna splicing. lesson menu join nagwa classes...