筛选得到 反式十八烯酸（TVA，Trans-Vaccenic Acid）可有效增强小鼠和人类原代 T 细胞的功能，并挽救 Jurkat T 细胞的 PD-L1–PD-1 依赖性耗竭，起到抗肿瘤的作用。▲ 饮食来源的 TVA 通过效应 CD8 + T 细胞增强抗肿瘤免疫 小贴士TVA 是一种长链脂肪酸，大量存在于反刍动物的脂肪和乳制品中（如牛肉、羊肉、...
[1] Nutrient found in beef and dairy improves immune response to cancer. Retrieved November 22, 2023 from https://www.eurekalert.org/news-releases/1008478 [2] Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity. Nature (2023). DOI: https://doi.org/10.1038/s41586-023-067...
Here we use a blood nutrient compound library-based screening approach to demonstrate that dietary trans-vaccenic acid (TVA) directly promotes effector CD8+ T cell function and anti-tumour immunity in vivo. TVA is the predominant form of trans-fatty acids enriched in human milk, but the human ...
trans-Vaccenic acid 是一种前体物质,能够在瘤胃中合成饱和脂肪酸,在组织水平合成共轭亚油酸。回复等你来答 阿拉丁试剂官网 罗恩试剂是哪个公司的 罗恩试剂是哪个国家的 玻璃管封装的氯金酸如何打开? 标准葡萄糖溶液需自己配置是吗 DMPT有什么用途 中国实验室和分析用途中禁止使用四氯化碳 、 不推荐使用四氯化碳清单 ...
trans-Vaccenic acid CAS No. : 693-72-1 MCE 站:trans-Vaccenic acid 产品活性:trans-Vaccenic acid 是一种前体物质,能够在瘤胃中合成饱和脂肪酸,在组织水平合成共轭亚油酸。 研究领域:Metabolic Enzyme/Protease 作用靶点:Endogenous Metabolite 相关产品:Human Endogenous Metabolite Compound Library | Natural Produc...
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Mice were fed pure trans11 octadecenoic acid (trans-vaccenic acid; TVA) to determine whether it is desaturated to cis9, trans11 octadecadienoic acid, a predominant isomer of conjugated linoleic acid (CLA). In a preliminary trial, 12% of the TVA consumed during a 2-wk feeding period was ...
英文名称:trans-vaccenic acid CAS号:693-72-1 EINECS号:211-758-9 分子式:C18H34O2 分子量:282.4614 InChI:InChI=1/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h8-9H,2-7,10-17H2,1H3,(H,19,20)/b9-8+ ...
常用名反式-11-十八烯酸英文名trans-Vaccenic acid CAS号693-72-1分子量282.461 密度0.9±0.1 g/cm3沸点398.2±11.0 °C at 760 mmHg 分子式C18H34O2熔点44℃ MSDS中文版美版闪点295.0±14.4 °C 符号 GHS07信号词Warning 如对规格有其他要求,或想要更低折扣,请联系线上客服。
Trans vaccenic acid (TVA; trans-11 18:1) is a positional and geometric isomer of oleic acid and it is the predominant trans isomer found in ruminant fats. TVA can be converted into cis-9, trans-11 conjugated linoleic acid (c9, t11-CLA), a CLA isomer that has many beneficial effects,...