Direct interaction of the trans-Golgi network membrane protein, TGN38, with the F-actin binding protein, neurabin. J Biol Chem. 1999; 274 :30080–6.Stephens DJ, Banting G. Direct interaction of the trans- Golgi network membrane protein, TGN38, with the F-actin binding protein, neurabin....
Golgi apparatus n. A network of stacked membranous vesicles, present in most living cells, that stores and modifies proteins and other macromolecules and transports them within the cell or excretes them from the cell. Also calledGolgi body,Golgi complex. ...
Vesicle Formation at the Plasma Membrane and Trans-Golgi 在质膜和高尔基体囊泡的形成.ppt,Vesicle Formation at the Plasma Membrane and Trans-Golgi Network: The Same but DifferentM. A. McNiven, et al., Science 313, 1591 (2006)Department of Biochemistry and
The Golgi complex receives nascent proteins that have been carried from the ER in vesicles. Multiple membrane stacks, transport vesicles, and the trans-Golgi network (TGN) form the Golgi complex. The cis-Golgi is closest to the nucleus, whereas the trans-Golgi is the most distal. Unlike the...
The GTP-binding protein ADP-ribosylation factor (ARF) initiates clathrin-coat assembly at the trans-Goli network (TGN) by generating high-affinity membrane-binding sites for the AP-1 adaptor complex. Both transmembrane proteins, which are sorted into the assembling coated bud, and novel docking pr...
TGN exportThe sorting and distribution to different final destinations of roughly a third of the membrane and secreted proteins occurs at the level of the Trans〨olgi Network (TGN). This TGN mission involves efficient mechanisms of cargo recognition and activation of specific signaling pathways. This...
Consortin is located at the trans-Golgi network (TGN), in tubulovesicular transport organelles, and at the plasma membrane. It directly interacts with the TGN clathrin adaptors GGA1 and GGA2, and disruption of this interaction by expression of a consortin mutant lacking the acidic cluster鈥揹...
Constitutive endocytic recycling is a crucial mechanism allowing regulation of the activity of proteins at the plasma membrane and for rapid changes in their localization, as demonstrated in plants for PIN-FORMED (PIN) proteins, the auxin transporters. To identify novel molecular components of endocytic...
Observations of Golgi fragmentation upon introduction of G protein βγ (Gβγ) subunits into cells have implicated Gβγ in a pathway controlling the fission at the trans-Golgi network (TGN) of plasma membrane (PM)-destined transport carriers. However, the subcellular location where Gβγ acts...
Lipid-dependent protein sorting at the trans-Golgi network This review highlights lipid involvement in membrane sorting at the TGN. Data support the role of lipid rafts in cargo segregation and carrier formation. ... MA Surma,C Klose,S Kai - 《Biochimica Et Biophysica Acta》 被引量: 128发表...