trans‐Golgi networkMembrane contact sites (MCSs) between different organelles have been identified and extensively studied over the last decade. Several classes of MCSs have now well〆stablished roles, but the contacts between the endoplasmic reticulum (ER) and the trans﹕ide of the Golgi network ...
(1994). Vacuolar ATPase inactivation blocks recycling to the trans-Golgi network from the plasma mem- brane. FEBS Lett. 345, 61- 66.Reaves B & Banting G (1994) Vacuolar ATPase inactivation blocks recycling to the trans-Golgi net- work from the plasma membrane. FEBS Lett. 345:61-66....
Molecular Membrane BiologyWang Y, Tai G, Lu L, Johannes L, Hong W, Tang BL (2005) Trans-Golgi network syntaxin 10 functions distinctly from syntaxins 6 and 16. Mol Membr Biol 22:313-325.Y. Wang, G. Tai, L. Lu, L. Johannes, W. Hong, B.L. Tang, trans-Golgi network syntaxin ...
TGN exportThe sorting and distribution to different final destinations of roughly a third of the membrane and secreted proteins occurs at the level of the Trans〨olgi Network (TGN). This TGN mission involves efficient mechanisms of cargo recognition and activation of specific signaling pathways. This...
Multiple membrane stacks, transport vesicles, and the trans-Golgi network (TGN) form the Golgi complex. The cis-Golgi is closest to the nucleus, and the trans-Golgi is the most distal. Unlike the ER, the cisternae of the Golgi stacks are not contiguous and their widths are not uniform. ...
Golgi apparatus n. A network of stacked membranous vesicles, present in most living cells, that stores and modifies proteins and other macromolecules and transports them within the cell or excretes them from the cell. Also calledGolgi body,Golgi complex. ...
Consortin is located at the trans-Golgi network (TGN), in tubulovesicular transport organelles, and at the plasma membrane. It directly interacts with the TGN clathrin adaptors GGA1 and GGA2, and disruption of this interaction by expression of a consortin mutant lacking the acidic cluster鈥揹...
The NLRP3 inflammasome, which has been linked to human inflammatory diseases, is activated by diverse stimuli. How these stimuli activate NLRP3 is unknown. Here we show that different NLRP3 stimuli lead to disassembly of the trans-Golgi network (TGN). NL
Myosin 1b promotes the formation of post-Golgi carriers by reg- ulating actin assembly and membrane remodelling at the trans-Golgi network. Nat. Cell Biol. 13:779-789. https://doi.org/10.1038/ncb2262Almeida, C. G., Yamada, A., Tenza, D., Louvard, D., Raposo...
This polarity is in part generated in the trans- Golgi network (TGN), where the proteins and lipids destined for the individual plasma membrane domains are sorted into distinct vesicle carriers (Griffiths and Simons 1986; Wandinger-Ness et al. 1990)....