A. et al. Unsupervised trajectory analysis of single-cell rna-seq and imaging data reveals alternative tuft cell origins in the gut. Cell systems (2017).Herring CA, Banerjee A, McKinley ET, Simmons AJ, Ping J, Roland JT, Franklin JL, Liu Q, Gerdes MJ, Coffey RJ, Lau KS (2017) ...
文章标题:OmicVerse: a framework for bridging and deepening insights across bulk and single-cell sequencing 发表期刊:Nature Communication 发表日期:16 July 2024 研究背景与意义 单细胞测序可用于trajectory analysis探索细胞发育和分化过程,但是由于测序平台的技术限制,测序过程中通常会有偏好地遗漏部分细胞类型。这...
Genome-wide identification of single-cell transcriptomic responses of drugs in various human cells is a challenging issue in medical and pharmaceutical research. Here we present a computational method, tensor-based imputation of gene-expression data at t
If you would like to use your own Single Cell Gene Expression data to run the velocity analysis in this guide, you need theoutput directoryfrom Cell Ranger (including theouts/subdirectory). Analysis steps Step 1. Export projection and clusters from Loupe Browser ...
文献分析 tradeSeq Trajectory-based differential expression analysis for single-cell sequencing data 原文pdf连接 https://www.nature.com/articles/s41467-020-14766-3#Sec23 摘要 轨迹推断通过研究基因表达的动态变化,从根本上增强了单细胞 RNA-seq 研究。在轨迹推断的下游,重要的是发现(i)与轨迹中的谱系相关...
利用单细胞转录组测序(single-cell RNA-seq)技术对相应的样本进行测序后,就可基于单细胞测序数据具体研究不同细胞状态间的转换过程,中文常称作细胞轨迹的构建或拟时间序列的构建,英文叫cell trajectory/lineage and pseudotime reconstruction/inference。其中pseudotime,中文翻译为拟时间, 一种假定的时间序列。这种类型的单...
Fig. 3: Single-cell pseudotime trajectory analysis of immune cells along HCC progression. aPseudotime trajectory ordering of tumour-infiltrating T cells along tumour progression.bPseudotime trajectory ordering of tumour-infiltrating NK cells along tumour progression.cPseudotime trajectory ordering of tumour-...
cell; EBC, epidermal bladder cell; PP, phloem parenchyma; GMC, guard mother cell; u.k., unknown Full size image Annotation of cell types based on the analysis of GO enrichment and KEGG Due to the lack of studies on cell types inquinoaleaves at the single-cell level, there is no ...
cell progenitors and aligned them with developmentally cued regulatory signaling including IL-7/STAT5 and cellular events such asimmunoglobulinrearrangement, highlighting checkpoints across which regulatory signals are rewired paralleling changes in cellular state. This study provides a comprehensive analysis ...
Single cell trajectory detection. Contribute to dpeerlab/Palantir development by creating an account on GitHub.