These results suggest that beef cattle terrain-use traits are polygenic and may be pleiotropic with other production traits.doi:10.1016/j.livsci.2019.103900C F PierceS E SpeidelS J ColemanR M EnnsM G ThomasLivestock Science
These regions confirmed the polygenic nature of the traits being studied and pointed to genes of interest. For BB, the most important chromosome in terms of local regions is often located on bovine chromosome (BTA) 14. However, the important regions are spread across few different BTA’s in ...
Although conditional P-values are often proportional to marginal P-values, it is possible that cell type with higher marginal P-value results in less conditional P-value for a pair of cell types (i.e. pb,a < pa,b). Therefore, when PSa,b < 0.2 and PSb,a ≥ 0.2, the...
In the context of human traits, most often only additive genetic factors are considered for the genetic variance (parameter \({\sigma }_{A}^{2}\), estimate VA) and the ratio of variances is the narrow-sense heritability. Latent model A collection of formalized assumptions to describe a ...
Selection often favours different phenotypes in males and females, driving the evolu- tion of sex-specific genetic architectures that facilitate sexual dimorphism. Previous theory based on single-locus models has shown how such architecture can evolve through modifiers of gene expres- sion and allelic ...
While dominant and recessive traits may seem straightforward, note that not all traits have this simple inheritance pattern. Other types ofgenetic inheritancepatterns includeincomplete dominance, co-dominance, andpolygenic inheritance. Due to the complexity of how genes are inherited, specific patterns can...
[24]. A major challenge is combining large numbers of traits that are polygenic in nature [25]. While marker-assisted selection (MAS) has proven itself a useful tool in crop improvement programs, the approach is most effective when targeting a small number of genes with large effect, such ...
Many human traits are controlled by more than one gene. These traits are calledpolygenic traits. The alleles of each gene have a minor additive effect on the phenotype. There are many possible combinations of alleles, especially if each gene has multiple alleles. ...
Most often, SNPs are biallelic, which means that the nucleotide will be one of two different alleles. Heritable A characteristic or trait that has a portion of variability that is accounted for by genetic factors. Haplotypes Sections of commonly varying or linked chromosomal material said to be ...
Several genes putatively under positive selection in the Maniq are associated with GWAS traits like type II diabetes mellitus, body height, or BMI-adjusted waist circumferences (Fig. 1) suggesting the possibility of polygenic selection. If polygenic selection has indeed contributed to the so-called...