These regions confirmed the polygenic nature of the traits being studied and pointed to genes of interest. For BB, the most important chromosome in terms of local regions is often located on bovine chromosome (BTA) 14. However, the important regions are spread across few different BTA’s in ...
Most often, SNPs are biallelic, which means that the nucleotide will be one of two different alleles. Heritable A characteristic or trait that has a portion of variability that is accounted for by genetic factors. Haplotypes Sections of commonly varying or linked chromosomal material said to be ...
Genome-wide association studies (GWAS) have cataloged many significant associations between genetic variants and complex traits. However, most of these findings have unclear biological significance, because they often have small effects and occur in non-
Their work revealed that transgressive segregation can lead to a wider range of trait values than expressed by the parents, complex traits are often genetically correlated and evolve in tandem, and local adaptation is typically polygenic, that is, controlled by many loci of small effect (Clausen ...
polygenic nature of the traits being studied and pointed to genes of interest. For BB, the most important chromosome in terms of local regions is often located on bovine chromosome (BTA) 14. However, the important regions are spread across few different BTA’s in TC. Quantitative trait loci ...
While dominant and recessive traits may seem straightforward, note that not all traits have this simple inheritance pattern. Other types ofgenetic inheritancepatterns includeincomplete dominance, co-dominance, andpolygenic inheritance. Due to the complexity of how genes are inherited, specific patterns can...
Many human traits are controlled by more than one gene. These traits are calledpolygenic traits. The alleles of each gene have a minor additive effect on the phenotype. There are many possible combinations of alleles, especially if each gene has multiple alleles. ...
Long-term selection experiments are a powerful tool to understand the genetic background of complex traits. The longest of such experiments has been conducted in the Research Institute for Farm Animal Biology (FBN), generating extreme mouse lines with in
Carcass traits are regulated by polygenic effects [4,5]. Transcriptome sequencing (RNA-seq) revealed differential expression ofCRELD1andDNAJC30in the breast muscle of white recessive rock chickens compared to Xinghua chickens [6]. RNA-seq analysis identifiedPRKG2as an important candidate gene assoc...
In the context of human traits, most often only additive genetic factors are considered for the genetic variance (parameter \({\sigma }_{A}^{2}\), estimate VA) and the ratio of variances is the narrow-sense heritability. Latent model A collection of formalized assumptions to describe a ...