While theory often considers the effects of resource availability and disturbance as orthogonal (e.g., CSR theory2), these drivers are often confounded in real ecosystems. Agricultural systems in particular, tend to be found on a continuum between low intensity (low disturbance, no nutrient input)...
The results did not bear out H1, as there was no difference between pilots and controls in the Self-control factor of trait EI. Self-control has been linked to the ability to maintain situational awareness and control35,36,37. Despite the null result, it is worth noting that Self-control ...
factor in terms of normal genetic variation, reflecting the fact that the cost-benefit tradeoffs associated with proactive and reactive control might be adaptively optimized to certain environmental niches or have other selection advantages[58]. The COMT allele is a promising candidate genetic mechanism...
However, research has shown that early experience can be a critical factor in shaping an individual's plasticity to later environmental factors. In other words, plasticity itself can be investigated as a developing trait that reflects the combined action of an individual's genes and previous ...
(such as the presence of long-range regulatory regions containing transcription factor–binding sites), it will be challenging and time-consuming to characterize the exact underlying mechanisms. Finally, the relatively subtle effects detected on the phenotype of interest also require meticulous functional...
[44] enrichment of tissue-specific methQTLs in enhancer elements and transcription factor binding sites indicating an enhancer element in B cells and in the B lymphocyte cell line GM12878 (Fig.5C). Analogously, we associated the tissue-specific and shared methQTL SNPs and CpGs with overlapping ...
While "protein ubiquitination" and "apoptosis signaling" pathways were common to both the cell lines, the observed patterns of protein expression suggest that the evasion of apoptosis in each tumorigenic cell line occurs via different mechanisms. Evidently, apoptosis is regulated in BT474 via down re...
based on the posterior predictive p-value (PPP-value). Compared with the typical conservatism of PPP-value, the RE value measures the discrepancy effectively. Simulated and real data sets with different itemnumbers, degree of sparseness, sample sizes, and factor dimensions are studied to ...
We conduct a series of follow-up analyses to examine whether the degree of pleiotropy of genetic variants may be related to functional mechanisms, including cis-regulatory effects, chromatin states, transcription factor (TF) binding, and enhancer-gene connections. We further provide detail ...
factor2. These complications can be overcome by adopting functional traits in addition to the traditional species-based approach2,3,4. The functional trait approach is centred around the environmental filtering and habitat templet concepts2,5,6. Environmental conditions select for species with certain ...