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Increased level of methemoglobin, which is inactive in oxygen transport, was also seen. The rate of heme breakdown increased resulting in the release of free iron. Exposure to NiCl2 led to considerable cell lysis, indicating damage to the erythrocyte membrane. This was supported by the ...
Hemosiderin is a protein complex that stores iron in cells and is notably present in macrophages due to their phagocytosis of hemoglobin from extravasated blood, often seen in hematomas associated with an injury [109]. Iron-laden cells in a child’s meninges are often associated with non-accide...
Pyridoxine is also absorbed in the small intestine, and any excess is excreted in the urine. Deficiency can develop in two or three weeks. Like vitamin B2, it is active in the metabolism of amino acids. It also plays a role in making neurotransmitters-the chemicals that brain cells use to...