However, the clinical benefit from cMet‐targeted therapy has been limited. We developed a novel cMet‐targeted 'third‐generation' ADC, TR1801‐ADC, that was optimized at different levels including specificity, stability, toxin–linker, conjugation site, and efficacy. Our nonagonistic cMet antibody...
However, clinical benefit from c-Met targeted therapy has been limited up to this point. We developed an optimized c-Met targeted antibody drug conjugate TR1801-ADC that utilized optimization at all steps including specificity, stability, internalization, toxin linkers, conjugation site, PK, and in...