The invention discloses an application of a TPO (thrombopoietin) receptor agonist in promoting homing of HSCs (hematopoietic stem cells). The TPO receptor agonist can effectively promote homing of the HSCs after a bone marrow transplantation operation and further can be effectively used for ...
These results show that TPO can directly control signaling pathway leading to repair of HSC's DNA and open new avenues for TPO agonist using. They can be used to protect HSC before radio- or chemo-therapies and to minimize development of secondary acute myeloid leukemia. Expression of Mpl ...