Methods: To study the role of EC cells in the GI tract, we have generated an EC cell-specific tamoxifen inducible Cre line (Tph1CreERT2/+), a reporter mouse (Tph1CreERT2/+;Rosa26tdTom/+), and an EC cell depleted mouse (Tph1CreERT2/+;Rosa26DTA/+). We examined changes of the...