For long-term storage, ≤‑20° C is recommended. Product is stable at ≤ ‑20° C for at least 1 year. Background: Tryptophan Hydroxylase 1/TPH-1 Tryptophan hydroxylase (TPH) is a 51 kDa, 444 amino acid (aa) enzyme that belongs to the pterin-dependent, aromatic amino-acid hydroxy...
Invivo SERM-beta1 and 2 are brain penetrant and display dose dependent efficacy in the murine dorsal raphe assays for induction of tryptophan hydroxylase mRNA and progesterone receptor protein. These compounds show activity in the murine forced swim test and promote hippocampal neurogenesis acutely in...
Also, to probe into non-bonding interactions in terms of affinity, hydrophilic interactions and hydrophobic interactions between these compounds and the gastric cancer cells line (PDB ID: 4oum) downloaded from protein data bank [28] via molecular docking. Download: Download high-res image (399KB)...