Due to unique amphiphilic structure, TPGS offers many essential properties such as solubilizer, penetration enhancer, stabilizer, emulsifier, antioxidant agent and protection of drug in micelles, which can be used for permeation of drug through skin or deposition of drug in skin. Especially, the ...
The molecular structure, drug loading efficiency, drug release kinetics and stability of the conjugate were characterized. The cellular uptake, intracellular distribution, and cytotoxicity were accessed by using MCF-7 breast cancer cells and C6 glioma cells as in vitro cell model. The conjugate showed...
dissolving vitamin E TPGS, medicines and organic macromolecular polymer, such as PLGA (poly(lactic-co-glycolic acid)), in an organic solvent; emulsifying, removing the organic solvent in a volatizing manner to obtain the drug-loaded porous drug carrier particles with a porous structure on the su...