Conventionaltoxicology testingfocuses on urine drug screening in adult populations. Applications of such testing often include emergency medicine, preemployment drug screening, and pain management testing. For these applications, laboratory testing plays a central role in employment or medical management of ...
Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental...
Scholars have conducted a great deal of research on the LCSA theory. Though abundant achievements have been gained, it is still necessary to continue studying. At present, the research on LCSA focuses on the traditional LCA (E-LCA) and LCC methods, in theory or application aspects. The LCA...
Globally-adopted regulations for genotoxicity testing of small molecule drugs were previously described in ICH S2A (ICH, 1996a) and ICH S2B (ICH, 1996b). These guidelines provided details including the recommended battery of genetic toxicology assays, conduct of assays (e.g., test conditions, ...
testing facilities are adapting to these changes, implementing advanced technologies for accurate and efficient testing. The market for toxicology testing is expected to grow, driven by the increasing demand for drug screening in various industries and the need for early detection and treatment of ...
focuses on assessing potential effects on hormonal systems. These segments are essential in providing a comprehensive toxicological profile of drug candidates. The remaining applications segment encompasses various specialized toxicity tests, including genetic toxicity, ocular toxicity, and neurotoxicity testing,...
Human data on exposure and adverse effects are the most appropriate for human risk assessment, and modern toxicology focuses on human pathway analysis and the development of human biomarkers. Human biomonitoring and human placental transport studies provide necessary information for human risk assessment,...
Paediatric Toxicology is a branch of medical specialty which focuses on diagnosis, prevention oftoxic substancesand other adverse health effects in infants, children and adolescents. The adverse health effects occur due to environmental toxicants andbiological agents. Paediatric patients present unique affec...
However, the current study focuses on the immediate respiratory and immunological effects of silica and DEP, acknowledging their known carcinogenic potential but emphasizing non-cancerous outcomes due to the scope and duration of our investigation. While extensive research exists on the individual health...
Systematic reviews, pioneered in the clinical field, provide a transparent, methodologically rigorous and reproducible means of summarizing the available e