Bass cover of the song "Toxicity" originally by "System of a Down" written by John Dolmayan, Shavo Odadjian, Serj Tankian, Daron Malakian.© American Recordings and Columbia Records 2001.Licensed to SM, 视频播放量 607、弹幕量 0、点赞数 10、投硬币枚数 3
Arsenic is one of the most hazardous environmental contaminants, which adversely affects the dynamics of male reproductive system. Fisetin (FIS) is a bioactive flavonoid, which is known to exert strong antioxidative effects. Therefore, the current research was planned to evaluate the alleviative effica...
There is also a significant knowledge gap regarding the effects of major or active components of essential oils on the insect nervous system32,33. The possible target sites for the essential oil components thymol, eugenol, and carvacrol are gamma-amino butyric acid (GABA), octopamine/tyramine and...
Caffeine causes cardiac and central nervous system stimulation, which can be dangerous. Caffeine also affects the gastrointestinal tract and can cause stomach upset. While vomiting may remove some of the toxin from the body, too much vomiting can cause dehydration due to fluid loss. Pets may also...
monocytogenes shuts down the transcription of genes involved in heme/iron uptake and utilization. Furthermore, heme stress resulted in a massive increase in the transcription of a putative heme detoxification system, hrtAB, which is highly conserved in Gram-positive bacteria. As expected, we found ...
Almost 40% proteins were down-regulated in ZnO-NPs (10 mg L−1) exposed cell as compared to control. Metabolomics and system biology based pathway analysis, revealed that ZnO-NPs repressed a wide range of key metabolites involved in central carbon metabolism, cofactors synthesis, amino ...
However, a large fraction (>30% of initial dye concentration) of reactive dyes are hydrolyzed during dyeing processes and get discharged along with the effluents (Venkatachalam and Seralathan, 2017). The presence of reactive dyes in aquatic system has a detrimental impact on aquatic organisms and...
It totes electrons in the oxidative phosphorylation (OXPHOS) system -- the cell's perpetual motion machine. In other words messing with OXPHOS can mess up mitochondrial function. Doctors who prescribe statins already know they pose a long-term or high-dose mitochondrial threat manifested as muscle...
RAN translation at CGG repeats induces ubiquitin proteasome system impairment in models of fragile X-associated tremor ataxia syndrome. Hum. Mol. Genet. 24, 4317–4326 (2015). Article CAS PubMed PubMed Central Google Scholar Green, K. M. et al. RAN translation at C9orf72-associated repeat...
*email: mk8363@nyu.edu Scientific Reports | (2022) 12:8140 | https://doi.org/10.1038/s41598-022-12191-8 1 Vol.:(0123456789) www.nature.com/scientificreports/ autophagy and the ubiquitin proteasome system (UPS)11,12 as well as compromised endolysosomal f unction13–15. TDP-43, a ...