Significance of CSF total neopterin and biopterin in inflammatory neurological diseases. J Neurol Sci 1992; 111:65 - 72.Furukawa Y, Nishi K, Kondo T, Tanabe K, Mizuno Y. Significance of CSF total neopterin and
Cerebrospinal fluid (CSF) has been used to identify biomarkers of neurological disease. CSF protein biomarkers identified by high-throughput methods, however, require further validation. While Western blotting (WB) is well-suited to this task, the lack of a validated loading control for CSF WB lim...
6–9 are forest plots depicting effects of omega-3, omega-6 and total PUFA on cancer-related outcomes, Supplementary Fig. 10 the funnel plot for effects of total PUFA on cancer diagnosis, Supplementary Figs. 11–15 further forest plots, Supplementary Tables 2–6 detail results of all meta-...
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“Aim:Currently, there exist no curative treatments for neurodegenerative disorders. Recently, there has been a resurgence of interest in the use of medicinal cannabis to improve neurological conditions. Methods:A 12-month, open label, dose-finding, safety and efficacy study was conducted including ...
In Omega Fatty Acids in Brain and Neurological Health 199–212. (Academic Press, 2019). 19. McNamara, R. K. Role of omega-3 fatty acids in the etiology, treatment, and prevention of depression: current status and future directions. J. Nutr. Intermed. Metabol. 5, 96–106 (2016). 20...
Especially in oncologic therapies, and also in neurological diseases, many new targeted therapies have been introduced in the last decade [43, 56]. This so-called potential of total-body dynamic imaging can improve the understanding of PK and PD of investigational drugs and reduce the risk in ...
Strengths and Limitations Strengths of the present study include a direct comparison of multiple dietary patterns, long-term and repeated measures of diet, multiple racial and ethnic groups, and observed associations between dietary quality scores and respiratory and neurological disease mortality. However...
Moreover, more detailed exclusion criteria for patient selection beyond underlying neurological conditions could have yielded clearer results, given the characteristics of older patients with various underlying medical conditions. However, despite the small sample size, our results are encouraging, showing ...
Despite early diagnosis and compliance with phenylalanine (Phe)-restricted diets, many individuals with phenylketonuria (PKU) still exhibit neurological changes and experience deficits in working memory and other executive functions. Suboptimal choline intake may contribute to these impairments, but this rela...