Meiosis requires the formation of programmed DNA double strand breaks (DSBs), essential for fertility and for generating genetic diversity. DSBs are induced by the catalytic activity of the TOPOVIL complex formed by SPO11 and TOPOVIBL. To ensure genomic
Moreover, the presence of the fluorine atom slightly out of the active site of both Topo I/II (indicated by the blue highlight on the fluorine atom in both Figs. 4 and 8 suggesting that the size of the substitution is essential in those group of compounds as increased size will not ...
Elastic folding, a phenomenon widely existing in nature, has attracted great interests to understand the math and physical science behind the topological transition on surface, thus can be used to create frontier engineering solutions. Here, we propose a topo-optical sensing strategy with ultra-high...
Original TA Cloning® Kit Dual Promoter •≥80% recombinants•Blue/white color screening•Dual Sp6 and T7 promoter/primers sites for in vitro transcription K2050-01K2060-01 TOPO® Cloning(5 minutes) Topoisomerase Various •Fast cloning directly into an expression vector All the TOPO Ex...
Blue underground cave theme By 1890lindada ( Free ) It is an isolated, magical place. In a cave, there are many stones, have clear water to flow out from the cracks in the stone. As like a stream. The whole background is faint, it ... ...
Topo TA克隆方法(Topo TA Cloning Kit) Topo TA克隆原理与TA克隆一样,唯一不同的是TA克隆用的是T4连接酶把PCR片断连接到T载体上,而Topo TA Cloning用的是DNA Topoisomerase。 Topoisomerase的用途一般使用在复制DNA前把超螺旋DNA切割使之解旋后,再连接成线性DNA。 Topo TA克隆即使用Topoisomerase高效连接的特性把含...