Sepideh Khoee, Morteza Yaghoobian, in Nanostructures for Drug Delivery, 2017 3.2 Large Unilamellar Vesicles (LUV) This type of noisome (100–3000 nm) has a high aqueous phase-to-surfactants compartment ratio; accordingly the bioactive material can be entrapped with a very economical use of memb...
These models are then extended to the multiple dosing situations for each of these types of drug delivery. The principles behind other more advanced PK modeling concepts and approaches also are included at the end of this chapter. 10.1.2 Basic Pharmacokinetic Terms A few basic terms must be ...
12 Step RecoveryAbuse SurvivorsAchieving GoalsAddictionADHDADHDAlcohol and Drug FreeAlcoholismAllergiesAlzheimer's DiseaseAnger ManagementAnxietyAnthony RobbinsArthritisAsperger SyndromeAuthenticityAutismMoms of Autistic KidsAutism Spectrum DisordersAutism Spectrum DisordersAutoimmune DiseaseBreast CancerRelationship AdviceBi...
A "black box" warning is the most serious type of warning on prescription drug labeling. The warning emphasizes that patients of all ages taking antidepressants should be closely monitored, especially during the initial weeks of treatment. Possible side effects to look for are worsening depression,...
from the sequencing of the virus is truly remarkable in that the shortness timeline for a previous vaccine was four years. This inspiring achievement from the federal research establishment, American pharmaceutical companies, and the FDA should provide an accelerated pathway for future ...
enhanced recovery of petroleum reservoirs, packed bed heat exchangers, drying technology, catalytic reactors, petroleum industries, geothermal systems, tissue engineering, drug delivery, avionics, miniature refrigerators, nanoporous materials, microtextured surfaces for enhanced boiling, particle migration and de...
glycans are often overlooked during drug development. Recently, the emergence ofcoronavirusdisease 2019 (COVID-19) has revealed that glycans on viral glycoproteins are critical for engagement with host receptors [23–25]. This event has put the spotlight on the importance of glycans in the context...
For example, caffeine, present in many beverages, is able to enter the brain and disrupt sleep. The existence of this barrier is an important issue for drug developers and much work has gone into the development of test tube models for the blood-brain barrier. Similarly, much work has also...
47,48 This cancer cell dependence or addiction should provide a window for drug specificity for the malignant cell compared with normal cells. Targeted therapeutics that take advantage of genetic abnormalities should, in theory, be more injurious to the malignant cell than to the normal cellular ...
groups of bacteria and even yeasts. The API 50 CHL test strip enables the determination of the fermentative ability of 49 different carbohydrates by an isolated strain. The system is standardized, and every step is exactly defined, e.g., for inoculation of each of the 50 wells in the strip...